Assessing the economic burden of breast cancer in a US managed care population
Assessing the economic burden of breast cancer in a US managed care population
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DOI：
10.1007/s10549-007-9650-4
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发表时间：
2008-05-01
影响因子：
3.8
通讯作者：
Amonkar, Mayur M.
中科院分区：
文献类型：
--
作者：
Barron, John J.;Quimbo, Ralph;Amonkar, Mayur M.
Background Breast cancer is the most commonly diagnosed non- skin cancer and second leading cause of cancer deaths among women in the US. This study compared healthcare resource utilization and costs in women with breast cancer to a control group in a managed care population.Material and methods Women 18 years with breast cancer were identified using ICD- 9 codes from claims databases of five US health plans during 2004. A randomly matched control group of women without cancer served as a comparator group. Healthcare costs included all medical and pharmacy costs during the year. Comparisons were made using per patient per month ( PPPM) costs ( total costs per patient within 2004 calendar year/ months of eligibility). Results 10,697 women ( mean age 55 years) with breast cancer were identified ( prevalence of 250 per 100,000) in 2004, with prevalence increasing with age. Mean attributable PPPM costs associated with breast cancer were $ 2,896 ( median = $ 1,940) with hospitalization contributing most of the costs ($ 1,340), followed by pharmacotherapy ($ 537), and surgical intervention ($ 470). Mean unadjusted allcause PPPM total costs were $ 4,421 ( median = $ 2,964) compared to $ 3,352 ( median = $ 665) p < 0.0001) for cases and controls respectively. Multivariate analyses controlling for differences in comorbidities showed mean adjusted PPPM costs to be 2.28 times ( p < 0.0001) higher than non-breast cancer controls.Discussion This study demonstrated that breast cancer treatment was associated with substantial healthcare costs, driven mainly by hospitalizations. Projected annual costs for a breast cancer patient would be at least $ 12,828 higher than that for women without breast cancer based upon unadjusted cost differences.
