Increasing Diverticulosis in an Aging Population: A Colonoscopy-Based Study of 5-Year Trends in 26 463 Patients in Northern China.
Increasing Diverticulosis in an Aging Population: A Colonoscopy-Based Study of 5-Year Trends in 26 463 Patients in Northern China.
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老龄化人群中憩室病的增加：基于结肠镜检查的中国北方 26 463 名患者的 5 年趋势研究
DOI：
10.12659/msm.906864
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发表时间：
2018-05-06
期刊：
影响因子：
--
通讯作者：
Sun C
中科院分区：
文献类型：
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作者：
Yang F;Lin L;Jiang X;Lv H;Sun C
由于此类数据在中国北部地区很少，因此本研究的目的是确定在过去5年中憩室病的趋势。我们分别回顾了2011年1月至2015年12月的26463例患者(27558次检查，包括1095次重复结肠镜检查)。记录憩室的分布情况，分为右侧、左侧和双侧型。从年龄和逐年增加的角度分析了憩室病的趋势。此外，使用Logistic回归模型确定了憩室病的发生与年龄(≤39，40-59，≥60岁)和性别的关系。我们发现了1045例结肠憩室病，总患病率为3.8%(1045/27558)。右侧憩室占72.9%(693/951)。结肠憩室病的比例明显上升(趋势为P<；0.001)，从2011年的2.78%上升到2015年的4.98%(309/6208)。各年龄段的憩室病患者比例明显增加(P<；趋势为0.001)，且呈逐年上升趋势。无论分布如何，在≥60岁的患者中，憩室病的比例都高于年轻年龄组(趋势P<；0.001)。多因素分析显示，年龄和男性(P<；0.001)是憩室病的独立危险因素。中国北部的结肠憩室病一直在增加，那里正在快速老龄化。
Because such data are scarce in northern China, the purpose of this study was to determine trends in diverticulosis over the past 5 years. A total of 26 463 patients (27 558 examinations, including 1095 repeated colonoscopies) performed between January 2011 and December 2015 were reviewed respectively. The distributions of diverticulosis were recorded, which were classified as right-sided, left-sided, and bilateral type. The trends in diverticulosis were analyzed in terms of aging and yearly increase. Additionally, associations of the occurrence of diverticulosis with age (≤39, 40–59, and ≥60 years) and sex were determined using a logistic regression model. We identified 1045 patients with colonic diverticulosis, with an overall prevalence of 3.8% (1045/27 558). A preponderance of right-sided diverticulosis was demonstrated, accounting for 72.9% (693/951) of included subjects. The proportion of colonic diverticulosis increased significantly (P<0.001 for trend), from 2.78% (112/4028) in 2011 to 4.98% (309/6208) in 2015. The proportion of patients of all age groups with diverticulosis increased significantly (P<0.001 for trend) in correlation with yearly increase. There was a greater proportion of diverticulosis, regardless of the distribution, in patients aged ≥60 than in younger age groups (P<0.001 for trend). Multivariate analysis showed older age and male sex (P<0.001) were independent risk factor for diverticulosis. Colonic diverticulosis has been increasing in northern China, where rapid aging is ongoing.