Changes and trends in attack distributions and progression of dental caries in three age cohorts in Finland.
Changes and trends in attack distributions and progression of dental caries in three age cohorts in Finland.
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DOI：
10.1080/13595220152601792
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发表时间：
2001-01-01
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影响因子：
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通讯作者：
Virtanen, J I
中科院分区：
文献类型：
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作者：
Virtanen, J I
背景技术背景：据称有几个因素已经促成了龋齿，已经发生在近几十年来，在许多工业化countries.METHODS：一个回顾性队列设计的后续研究龋齿的趋势，在三个年龄组出生的十年除了从芬兰报道。受试者出生于20世纪60年代，70年代和80年代（n = 1275），每年通过他们的病历进行监测，并分析了龋齿发作（龋齿导致牙釉质或拔牙）的分布，程度和速度的变化。Logistic和Poisson回归技术进行检测的趋势和Kaplan-Meier生存率的方法进行了analysis.Results：观察到一个显着的减少龋齿和无病受试者的比例逐渐增加，对年轻的队列。Logistic回归分析显示了明显的趋势，队列效应的比值比（OR）分别为8.93 [95%置信区间（CI）= 7.95-10.04]和4.32（95% CI = 3.92-4.75），相对于1980年队列，年龄效应为1.44（95% CI = 1.42-1.46）。在疾病进展分析中发现了相似类型的队列和年龄效应（p < 0.0001）。比率分析显示，三个队列之间男女的统计学差异非常显著（p < 0.001）。龋齿的下降是一个持久的，尽管在最年轻的cohol.DISCUSSION观察到的delayations：结果表明，在龋齿的发病率导致delayations和提取的一个巨大的和持续的趋势。疾病进展的速度和程度发生了重大变化，这将不可避免地影响未来的公共卫生议程。
BACKGROUND: Several factors are claimed to have contributed to the decline in dental caries that has occurred over recent decades in many industrialised countries.METHODS: A retrospective cohort design follow-up study of trends in dental caries in three age cohorts born a decade apart is reported from Finland. Subjects born in the 1960s, 1970s and 1980s (n = 1275) were monitored annually through their patient records, and changes in the distribution, extent and rate of caries attack (caries leading to restorations or extractions) were analysed. Logistic and Poisson regression techniques were employed to detect trends and Kaplan-Meier survival methods were used for the rate analyses.RESULTS: A marked decrease in caries was observed and the proportion of disease-free subjects increased gradually towards the younger cohorts. Logistic regression analysis showed clear trends, in that the odds ratios (ORs) for the cohort effect were 8.93 [95% confidence interval (CI) = 7.95-10.04] and 4.32 (95% CI = 3.92-4.75) in the 1960 and 1970 cohorts, respectively, relative to the 1980 cohort, and that for the age (year) effect was 1.44 (95% CI = 1.42-1.46). Similar types of cohort and age effects (p < 0.0001) were found in the disease progression analyses. The rate analyses showed statistically highly significant differences between the three cohorts (p < 0.001) for both sexes. The caries decline was a lasting one, in spite of the delay in restorations observed in the youngest cohort.DISCUSSION: The results indicate a vast and continuous trend in the incidence of dental caries leading to restorations and extractions. Significant changes in the rate and extent of disease progression have taken place, which will inevitably affect the future public health agenda.