Predictors of glucose control in children and adolescents with type 1 diabetes: results of a cross-sectional study in Cameroon.
Predictors of glucose control in children and adolescents with type 1 diabetes: results of a cross-sectional study in Cameroon.
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DOI：
10.1186/s13104-017-2534-8
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发表时间：
2017-06-12
影响因子：
1.8
通讯作者：
Parhofer, Klaus G
中科院分区：
文献类型：
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作者：
Niba, Loveline L;Aulinger, Benedikt;Parhofer, Klaus G
背景：在撒哈拉以南非洲，1型糖尿病儿童的预后很差。许多人没有被诊断出来，而那些被诊断出来的人的预期寿命大大缩短（不到一年）。本研究的目的是确定儿童和青少年1型糖尿病患者血糖控制的预测因素。这项基于医院的横断面研究涉及76名儿童/青少年。（35名男孩和41名女孩，平均年龄15.1± 3.1岁），1型糖尿病患者纳入“儿童糖尿病变化”（CDiC）在喀麦隆西北部地区，为患有1型糖尿病的儿童提供了一个项目和诊所。糖化血红蛋白（HbA 1c）的数据来自参与者的医院记录。使用结构化问卷从参与者中获得有关社会人口学特征和糖尿病相关实践的信息。使用逻辑回归模型计算比值比（OR），以评估决定因素和良好血糖控制之间的关联。结果：研究人群的平均HbA 1c为10.3± 2.9%。双变量分析表明，母亲作为主要照顾者（OR 0.07，95%CI 0.02-0.2）、每天注射2次胰岛素（OR 0.2，95%CI 0.1-0.5）和良好的血糖监测（BGM）依从性（OR 0.1，95%CI 0.04-0.3）与母亲作为主要照顾者（OR 0.07，95%CI 0.02 - 0.2）之间存在显著性差异（p
BACKGROUND: In sub-Saharan Africa the prognosis of children with type 1 diabetes is poor. Many are not diagnosed and those diagnosed have a dramatically reduced life expectancy (less than one year). The purpose of this study was to identify the predictors of glucose control in children and adolescents with type 1 diabetes.METHODS: This hospital based cross-sectional study involved 76 children/adolescents (35 boys and 41 girls, mean age of 15.1±3.1years) with type 1 diabetes included in the "Changing Diabetes in Children" (CDiC) program and attending the clinics for children living with type 1 diabetes in the North West Region of Cameroon. Data on glycosylated haemoglobin (HbA1c) was obtained from hospital records of participants. Information on socio-demographic characteristics and diabetes related practices were obtained from participants using a structured questionnaire. Odds ratios (OR) were calculated using logistic regression models to assess the association between determinants and good glyceamic control.RESULTS: The study population had a mean HbA1c of 10.3±2.9%. Bivariate analysis indicated that having a mother as the primary caregiver (OR 0.07, 95% CI 0.02-0.2), being on 2 daily insulin injections (OR 0.2, 95% CI 0.1-0.5) and good blood glucose monitoring (BGM) adherence (OR 0.1, 95% CI 0.04-0.3) were significantly (p