DEPRESSION OF RECURRENT INHIBITION OF EXTENSOR MOTONEURONS BY ACTION OF GROUP 2 AFFERENTS
DEPRESSION OF RECURRENT INHIBITION OF EXTENSOR MOTONEURONS BY ACTION OF GROUP 2 AFFERENTS
复制标题
DOI：
10.1016/0006-8993(77)90399-7
复制
发表时间：
1977-01-01
期刊：
影响因子：
2.9
通讯作者：
WOLF, E
中科院分区：
文献类型：
--
作者：
FROMM, C;HAASE, J;WOLF, E
在去大脑猫腹根细丝记录的强直性伸肌运动神经元上，研究了不同肌肉传入纤维输入对正常放电率（Fn）和恒定腹根刺激诱导的复发抑制量（Fn-Fi）的影响。通过对腓肠肌神经的分级电刺激和通过振动小腿三头肌（100 μ m振幅）来改变传入输入。当输入仅由Ia传入冲动组成时，如振动期间的情况，平均复发抑制Fn-Fi是神经强直期间的2.3倍，阈值为I组（TI）的1.8倍。这种强度一般兴奋所有组I和一些低阈值组II传入。在1.8 TI和8 TI之间，Fn-Fi降低了约50%。平均Fn略有增加和运动神经元的相位放电模式被招募时，刺激强度提高，以激发第II组传入，这些细胞从来没有被招募在振动和神经强直在1.8 TI。次级肌梭传入对伸肌运动神经元的抑制可能是通过减少反复抑制而发挥去抑制作用。
The influence of varying the muscular afferent fiber input on both the normal firing rate (Fn) and the amount of recurrent inhibition (Fn-Fi) induced by a constant ventral root stimulation was investigated on tonic extensor motoneurons recorded from ventral root filaments in decerebrate cats. The afferent input was varied by graded electrical stimulation of the gastrocnemius nerves and by vibrating the triceps surae muscle (100 .mu.m amplitude). When the input consisted solely of impulses in Ia afferents, as was the case during vibration, the mean recurrent inhibition Fn-Fi was 2.3 times greater than during nerve tetanization at 1.8 times threshold of group I (TI). This strength generally excited all group I and some low-threshold group II afferents. Between 1.8 TI and 8 TI, Fn-Fi decreased by some 50%. The average Fn increased slightly and motoneurons with a phasic discharge pattern were recruited when the stimulus strength was raised so as to excite group II afferents; these cells were never recruited during vibration and nerve tetanization at 1.8 TI. There may be a disinhibitory action of secondary muscle spindle afferents on extensor motoneurons by reducing the recurrent inhibition.