ENVENOMATION BY THE NORTHERN BLACKTAIL RATTLESNAKE (CROTALUS MOLOSSUS-MOLOSSUS) - REPORT OF 2 CASES AND THE INVITRO EFFECTS OF THE VENOM ON FIBRINOLYSIS AND PLATELET-AGGREGATION
ENVENOMATION BY THE NORTHERN BLACKTAIL RATTLESNAKE (CROTALUS MOLOSSUS-MOLOSSUS) - REPORT OF 2 CASES AND THE INVITRO EFFECTS OF THE VENOM ON FIBRINOLYSIS AND PLATELET-AGGREGATION
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DOI：
10.1016/0041-0101(82)90012-5
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发表时间：
1982-01-01
期刊：
影响因子：
2.8
通讯作者：
CORRIGAN, JJ
中科院分区：
文献类型：
--
作者：
HARDY, DL;JETER, M;CORRIGAN, JJ
在 2 例北黑尾响尾蛇 (C. molossus molossus) 毒入人类的案例中，被咬伤的肢体出现明显肿胀和瘀斑以及血小板减少症，还有 1 例出现低纤维蛋白原血症。治疗包括静脉注射。抗蛇毒血清、晶体溶液、新鲜冰冻血浆和冷沉淀，每种情况下均可恢复。体外研究表明，毒液具有纤溶和血小板聚集特性；虽然存在凝血作用，但不太明显。
In 2 cases of human envenomation by the northern blacktail rattlesnake (C. molossus molossus) there was marked swelling and ecchymosis of the bitten extremity and thrombocytopenia and in 1 case, hypofibrinogenemia. Treatment consisted of i.v. antivenin, crystalloid solutions, fresh frozen plasma and cryoprecipitates, with recovery in each case. In vitro studies showed that the venom had fibrinolytic and platelet aggregating properties;a coagulant effect, although present, was less marked.