Effects of a go/nogo task on event-related potentials following somatosensory stimulation
Effects of a go/nogo task on event-related potentials following somatosensory stimulation
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DOI：
10.1016/j.clinph.2003.09.013
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发表时间：
2004-02-01
影响因子：
4.7
通讯作者：
Kakigi, R
中科院分区：
文献类型：
--
作者：
Nakata, H;Inui, K;Kakigi, R
目的：研究GO/NOGO任务对体感刺激诱发的事件相关电位(ERPs)的影响。方法：记录9名受试者电刺激左手第二指(GO刺激)和第五指(NOGO刺激)后的事件相关电位(ERPs)。记录在3种条件下进行：控制、计数和移动。受试者被指示在计数中默数围棋刺激，并在运动中抓住右手对围棋刺激做出反应。结果：在所有条件下均可记录到N140，在计数和运动中记录到P300。NOGO刺激在140-200毫秒之间的平均波幅和NOGO-N140波幅在计数或运动方面明显低于GO刺激。在运动时，Nogo-P300的波幅大于Go-P300，但不计数。P300作用于FZ和Cz，但不适用于Pz。结论：本研究探讨了体感GO/NOGO任务对ERPs的影响，我们的研究结果与以往视觉和听觉GO/NOGO任务的结果非常相似。因此，我们认为与GO/NOGO任务相关的皮层活动不依赖于感觉模式。意义：本研究首次显示了GO/NOGO任务对体感诱发事件相关电位的影响。这些效应与视觉和听觉事件相关电位研究中的结果相似。(C)2003年国际临床神经生理学联合会。爱思唯尔爱尔兰有限公司出版。版权所有。
Objective: We investigated the effects of a go/nogo task on event-related potentials (ERPs) evoked by somatosensory stimuli.Methods: ERPs following electrical stimulation of the second (go stimulus) or fifth (nogo stimulus) left-handed digit were recorded from 9 subjects. The recordings were conducted in 3 conditions: Control, Count and Movement. The subjects were instructed to count the go stimuli silently in Count, and respond to the go stimuli by grasping right hands in Movement. Go and nogo stimuli were presented at an even probability.Results: N140 was recorded in all conditions and P300 in Count and Movement. The mean amplitudes of the nogo stimuli in the interval 140-200 msec and nogo-N140 amplitude were significantly more negative than those of the go stimuli in Count or Movement. Nogo-P300 was larger in amplitude than go-P300 in Movement but not Count. The effect of P300 was applied to Fz and Cz, but not at Pz.Conclusions: In the present study, effects of a somatosensory go/nogo task on ERPs were investigated, and our findings were very similar to those of previous studies using visual and auditory go/nogo tasks. Therefore, we suggest that cortical activities relating to go/nogo tasks are not dependent on sensory modalities.Significance: The present study showed for the first time the go/nogo effects on somatosensory-evoked ERPs. These effects were similar to those in visual and auditory ERP studies. (C) 2003 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.