Simul 5 - Free dynamic simulator of electrophoresis
Simul 5 - Free dynamic simulator of electrophoresis
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DOI：
10.1002/elps.200500756
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发表时间：
2006-03-01
期刊：
影响因子：
2.9
通讯作者：
Gas, B
中科院分区：
文献类型：
--
作者：
Hruska, V;Jaros, M;Gas, B
We introduce the mathematical model of electromigration of electrolytes in free solution together with free software Simul, version 5, designed for simulation of electrophoresis. The mathematical model is based on principles of mass conservation, acid-base equilibria, and electroneutrality. It accounts for any number of multivalent electrolytes or ampholytes and yields a complete picture about dynamics of electromigration and diffusion in the separation channel. Additionally, the model accounts for the influence of ionic strength on ionic mobilities and electrolyte activities. The typical use of Simul is: inspection of system peaks (zones), stacking and preconcentrating analytes, resonance phenomena, and optimization of separation conditions, in either CZE, ITP, or IEF.
