Distribution and Phylogeny of Light-Oxygen-Voltage-Blue-Light-Signaling Proteins in the Three Kingdoms of Life
Distribution and Phylogeny of Light-Oxygen-Voltage-Blue-Light-Signaling Proteins in the Three Kingdoms of Life
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DOI：
10.1128/jb.00923-09
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发表时间：
2009-12-01
影响因子：
3.2
通讯作者：
Jaeger, Karl-Erich
中科院分区：
文献类型：
--
作者：
Krauss, Ulrich;Minh, Bui Quang;Jaeger, Karl-Erich
植物和真菌通过不同的光感受器模块的作用对环境光刺激做出响应。响应于蓝色光区域的一个这样的类别由包含所谓的光-氧-电压（LOV）域作为传感器模块的光感受器构成。目前在真核生物中鉴定出四个主要的LOV家族：（i）植物向光蛋白，调节各种生理效应，如向光性、叶绿体移位和气孔开放;（ii）金色色素，介导光合藻类的光形态建成;（iii）植物昼夜光感受器zeitlupe（ZTL）/adagio（ADO）/黄素结合Kelch重复F-box蛋白1（FKF 1）家族;和（iv）真菌昼夜光感受器白领1（WC-1）。蓝光敏感的LOV信号传导模块也广泛存在于整个原核世界，并且最近报道了由细菌LOV光感受器介导的生理反应。因此，问题出现了亲和真核LOV光感受器系统之间的进化关系。我们使用贝叶斯和最大似然树重建方法来推断可能导致LOV域在原核生物和真核生物中广泛出现的进化情景。这里提出的系统发育研究表明细菌起源的LOV域的四个主要的真核LOV光感受器家族，而LOV传感器域最有可能从细菌中招募的过程中的质体和线粒体内共生。
Plants and fungi respond to environmental light stimuli via the action of different photoreceptor modules. One such class, responding to the blue region of light, is constituted by photoreceptors containing so-called light-oxygen-voltage (LOV) domains as sensor modules. Four major LOV families are currently identified in eukaryotes: (i) the plant phototropins, regulating various physiological effects such as phototropism, chloroplast relocation, and stomatal opening; (ii) the aureochromes, mediating photomorphogenesis in photosynthetic stramenopile algae; (iii) the plant circadian photoreceptors of the zeitlupe (ZTL)/adagio (ADO)/flavinbinding Kelch repeat F-box protein 1 (FKF1) family; and (iv) the fungal circadian photoreceptors white-collar 1 (WC-1). Blue-light-sensitive LOV signaling modules are also widespread throughout the prokaryotic world, and physiological responses mediated by bacterial LOV photoreceptors were recently reported. Thus, the question arises as to the evolutionary relationship between the pro-and eukaryotic LOV photoreceptor systems. We used Bayesian and maximum-likelihood tree reconstruction methods to infer evolutionary scenarios that might have led to the widespread appearance of LOV domains among the pro-and eukaryotes. The phylogenetic study presented here suggests a bacterial origin for the LOV domains of the four major eukaryotic LOV photoreceptor families, whereas the LOV sensor domains were most likely recruited from the bacteria in the course of plastid and mitochondrial endosymbiosis.