Sensitivity analyses of probabilistic and deterministic DTI tractography methodologies for studying arm muscle architecture.
Sensitivity analyses of probabilistic and deterministic DTI tractography methodologies for studying arm muscle architecture.
复制标题
研究手臂肌肉结构的概率性和确定性 DTI 纤维束成像方法的敏感性分析。
DOI：
10.1002/mrm.29862
复制
发表时间：
2024
影响因子：
3.3
通讯作者：
Ingo,Carson
中科院分区：
文献类型：
--
作者：
Joshi,Divya;Sohn,MHongchul;Dewald,JuliusPA;Murray,WendyM;Ingo,Carson
PurposeTo determine sensitivity profile of probabilistic and deterministic DTI tractography methods in estimating geometric properties in arm muscle anatomy. MethodsSpin-echo diffusion-weighted MR images were acquired in the dominant arm of 10 participants.在平行结构的肱二头肌（和羽状结构的尺侧腕屈肌）的两种不同肌肉结构中进行了确定性和概率性纤维束成像。肌束几何估计和束数进行了评价方面的纤维束成像转向角，多项式拟合顺序，和SNR。DTI纤维束成像估计的肌束长度进行了比较，从传统的尸体解剖和超声models.ResultsThe概率方法估计的肌束长度更接近传统方法报告的范围比确定性方法，最明显的肱二头肌（p> 0. 05），包括较长的，弧形的肌束。对于这两种方法，宽旋转角度（50º-90°）产生的束长度与传统方法非常一致，在尺侧腕屈肌中最明显（p> 0.05），由较短的羽毛状束组成。概率方法产生的分册至少是确定性方法的两倍。对于这两种方法，二阶拟合产生的完整束约为三阶拟合的两倍。在这两种肌肉中，随着SNR的降低，确定性纤维束成像产生较少的束，但一致的几何形状（p> 0.05），而概率纤维束成像产生了一致的数量，但改变几何形状的束（p< 0.001）。
PurposeTo determine the sensitivity profiles of probabilistic and deterministic DTI tractography methods in estimating geometric properties in arm muscle anatomy.MethodsSpin‐echo diffusion‐weighted MR images were acquired in the dominant arm of 10 participants. Both deterministic and probabilistic tractography were performed in two different muscle architectures of the parallel‐structured biceps brachii (and the pennate‐structured flexor carpi ulnaris. Muscle fascicle geometry estimates and number of fascicles were evaluated with respect to tractography turning angle, polynomial fitting order, and SNR. The DTI tractography estimated fascicle lengths were compared with measurements obtained from conventional cadaveric dissection and ultrasound modalities.ResultsThe probabilistic method generally estimated fascicle lengths closer to ranges reported by conventional methods than the deterministic method, most evident in the biceps brachii (p> 0.05), consisting of longer, arc‐like fascicles. For both methods, a wide turning angle (50º–90°) generated fascicle lengths that were in close agreement with conventional methods, most evident in the flexor carpi ulnaris (p> 0.05), consisting of shorter, feather‐like fascicles. The probabilistic approach produced at least two times more fascicles than the deterministic approach. For both approaches, second‐order fitting yielded about double the complete tracts as third‐order fitting. In both muscles, as SNR decreased, deterministic tractography produced less fascicles but consistent geometry (p> 0.05), whereas probabilistic tractography produced a consistent number but altered geometry of fascicles (p< 0.001).ConclusionFindings from this study provide best practice recommendations for implementing DTI tractography in skeletal muscle and will inform future in vivo studies of healthy and pathological muscle structure.