Ultrahigh-resolution optical coherence tomography with a fiber laser source at 1 microm.
Ultrahigh-resolution optical coherence tomography with a fiber laser source at 1 microm.
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DOI：
10.1364/ol.30.001171
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发表时间：
2005-05
期刊：
影响因子：
3.6
通讯作者：
Hyungsik Lim;Yi Jiang;Yimin Wang;Yu-Chih Huang;Zhongping Chen;F. Wise
中科院分区：
文献类型：
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作者：
Hyungsik Lim;Yi Jiang;Yimin Wang;Yu-Chih Huang;Zhongping Chen;F. Wise
我们报道了一种紧凑、高功率、基于光纤的近1微米超高分辨率光学相干断层扫描（OCT）光源。实际光源是基于短脉冲掺镱光纤激光器和在光子晶体光纤中产生连续光谱。宽带发射的平均功率为140兆瓦，在空气中提供2.1微米的轴向分辨率（在生物组织中<1.6微米）。宽频带的产生具有鲁棒性和高效性。我们展示了体外和体内生物组织的超高分辨率，时域OCT成像。
We report a compact, high-power, fiber-based source for ultrahigh-resolution optical coherence tomography (OCT) near 1 microm. The practical source is based on a short-pulse, ytterbium-doped fiber laser and on generation of a continuum spectrum in a photonic crystal fiber. The broadband emission has an average power of 140 mW and offers an axial resolution of 2.1 microm in air (<1.6 microm in biological tissue). The generation of a broad bandwidth is robust and efficient. We demonstrate ultrahigh-resolution, time-domain OCT imaging of in vitro and in vivo biological tissues.