Diurnal variations of cephalic exocrine pancreatic response in dogs.
Diurnal variations of cephalic exocrine pancreatic response in dogs.
复制标题
狗头部外分泌胰腺反应的昼夜变化。
DOI：
10.3177/jnsv.36.497
复制
发表时间：
1990
影响因子：
1.6
通讯作者：
Y. Itokawa
中科院分区：
文献类型：
--
作者：
I. Ohara;M. Kimura;Y. Itokawa
本研究的目的是确定口服蔗糖刺激对清醒犬胰腺分泌物日输出量的影响。用胃和十二指肠瘘制备体重9-11 kg的雄性比格犬。每天14：00训练动物进食足量的市售储备饲料以维持其体重。在9：00、13：00、15：00和18：00用100 ml含0.3 M蔗糖的0.5%琼脂溶液刺激味觉受体5 min。刺激前后每隔5 min收集一次胰液，测量体积流量和蛋白输出。因此，我们证明了每天的波动时间喂养不仅在胰腺的基础分泌物，但也在胰腺的味觉刺激的反应。这些结果表明，味觉刺激在动物的营养，至少在消化中的重要作用。
The purpose of this study was to determine effects of oral stimulation of sucrose on the diurnal output of pancreatic secretion in conscious dogs. Male beagle dogs weighing 9-11 kg were prepared with gastric and duodenal fistulae. Once a day at 14:00 the animals were trained to eat a sufficient amount of a commercial stock diet to maintain their body weight. Gustatory receptors were stimulated at 9:00, 13:00, 15:00, and 18:00 for 5 min with 100 ml of 0.5% agar solutions containing 0.3 M sucrose. Pancreatic juice was collected every 5 min before and after stimulation, and volume flow and protein output were measured. As a result, we demonstrated daily fluctuations timed by feeding not only in the pancreatic basal secretions but also in pancreatic responses to the gustatory stimulation. These results suggest the significant role of taste stimuli in the nutrition of, at least digestion in, animals.