Controlled release from a nanocarrier entrapped within a microcarrier.
Controlled release from a nanocarrier entrapped within a microcarrier.
复制标题
从捕获在微载体内的纳米载体中受控释放。
DOI：
10.1016/j.jcis.2006.05.046
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发表时间：
2006
影响因子：
9.9
通讯作者：
Papadopoulos,KyriakosD
中科院分区：
文献类型：
--
作者：
Rojas,EdithC;Sahiner,Nurettin;Lawson,LouiseB;John,VijayT;Papadopoulos,KyriakosD
This study illustrates the entrapment of the dye molecule fluorescein sodium salt (FSS) by hydrogel nanoparticles, which are in turn confined inside a water-in-oil-in-water double-emulsion globule, and its subsequent release by the action of the competing agent hydrochloric acid (HCl). Thus, a “double carrier” concept is being introduced in which a nanoscale delivery vehicle is being transported by a microscale delivery vehicle in order to simultaneously take advantage of both systems. This may facilitate storage and handling while protecting the active substance and improving its action upon application.
