Basic characteristics of chronic hypotension cases: A longitudinal follow-up study from 1958 through 1999
Basic characteristics of chronic hypotension cases: A longitudinal follow-up study from 1958 through 1999
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DOI：
10.1291/hypres.29.1
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发表时间：
2006-01-01
影响因子：
5.4
通讯作者：
Yano, K
中科院分区：
文献类型：
--
作者：
Akahoshi, M;Hida, A;Yano, K
关于慢性低血压的患病率、按年龄划分的血压趋势以及慢性低血压的基本特征，很少有流行病学研究。 1958 年至 1999 年间，日本对 13,370 名受试者（5,094 名男性和 8,276 名女性）进行了检查，其中 92 名受试者被确定为慢性低血压患者（11 名男性和 81 名女性），其收缩压（SBP，mmHg）低于 100 mmHg 持续 8 年或更长时间。在这组慢性低血压患者和 276 名年龄和性别匹配的对照组（33 名男性和 243 名女性）中，确定了 16 年期间的收缩压和体重指数（BMI，kg/m(2)）的趋势；在这 16 年期间，慢性低血压患者和对照组的年龄从 19 岁到 75 岁不等。比较慢性低血压患者与对照组末次检查时的BMI、心率（HR，bpm）、体温（℃）、Hb（g/dl）和肌酐（Cre，mg/dl）。慢性低血压患者以女性为主（男性0.2%，女性1.0%，p=0.001），其SBP和BMI随着年龄的增长而增加甚少。慢性低血压患者的 BMI (20.2 +/- 3.4)、BMI 调整后的 SBP (101 +/- 19)、HR (63 +/- 10)、体温 (36.7 +/- 0.3)、Hb (12.5 +/- 1.1) 和 Cre (0.81 +/- 0.13) 低于慢性低血压患者 (22.9 +/- 3.4、126)。对照中分别为 +/- 20、68 +/- 10、36.8 +/- 0.3、12.9 +/- 1.1 和 0.86 +/- 0.12）（p < 0.05）。目前的结果清楚地表明，慢性低血压患者以女性为主，BMI、HR、体温、Hb 和 Cre 较低，而且 SBP 不随年龄而增加。
Few epidemiological studies have been conducted on the prevalence, blood pressure trends by age, and basic characteristics of chronic hypotension. Among 13,370 subjects (5,094 men and 8,276 women) examined from 1958 to 1999 in Japan, 92 were identified as chronic hypotensives (11 men and 81 women) whose systolic blood pressure (SBP, mmHg) was lower than 100 mmHg for 8 or more years. Trends of SBP and body mass index (BMI, kg/m(2)) were determined over a 16-year period in this group of chronic hypotensives and 276 age- and sex-matched controls (33 men and 243 women); during this 16-year period, the chronic hypotensives and controls ranged in age from 19 to 75 years. BMI, heart rate (HR, bpm), body temperature (degrees C), Hb (g/dl), and creatinine (Cre, mg/dl) were compared between the chronic hypotensives and the controls at the last examination. The chronic hypotensives had a female preponderance (0.2% in men and 1.0% in women, p=0.001), and their SBP and BMI increased little with increasing age. BMI (20.2 +/- 3.4), BMI-adjusted SBP (101 +/- 19), HR (63 +/- 10), body temperature (36.7 +/- 0.3), Hb (12.5 +/- 1.1), and Cre (0.81 +/- 0.13) were lower in the chronic hypotensives than those (22.9 +/- 3.4, 126 +/- 20, 68 +/- 10, 36.8 +/- 0.3, 12.9 +/- 1.1, and 0.86 +/- 0.12, respectively) in controls (p < 0.05). The present results clearly show that chronic hypotensives have a female preponderance and low BMI, HR, body temperature, Hb, and Cre in addition to low SBP that does not increase with age.