The economic burden and symptom manifestations of chronic rhinosinusitis
The economic burden and symptom manifestations of chronic rhinosinusitis
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DOI：
10.1177/194589240301700106
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发表时间：
2003-01-01
期刊：
影响因子：
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通讯作者：
Bhattacharyya, N
中科院分区：
文献类型：
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作者：
Bhattacharyya, N
背景资料：本研究的目的是描述慢性鼻窦炎（CRS）患者的症状和经济负担。方法：采用调查工具对CRS成人患者进行前瞻性评估。确定CRS的主要和次要症状的症状评分、药物使用、CRS的医生访视和错过的工作日。结果：322例患者进行了前瞻性研究（平均年龄42.3岁）。鼻阻塞和面部充血是最常见和最严重的主要症状，头痛和疲劳是最常见和最严重的次要症状。在12个月的时间里，患者平均接受2.7个抗生素疗程，使用鼻用类固醇和处方抗组胺药分别为18.3周和16.3周。平均医疗资源成本为921美元/患者年。CRS平均每12个月造成4.8天的误工。CRS的总经济成本为1539美元/patient.Conclusion：鼻和面部症状占主导地位的全身和口咽症状的CRS。重大的医疗资源支出和全球经济成本伴随CRS。
Background: The aim of this study was to delineate patient symptoms and economic burdens of chronic rhinosinusitis (CRS).Methods: Adult patients with CRS were assessed prospectively with a survey instrument. Symptom scores for major and minor symptoms of CRS, medication use, physician visits for CRS, and work days missed were determined. Cost analyses were conducted.Results: Three hundred twenty-two patients were studied prospectively (mean age, 42.3 years). Nasal obstruction and facial congestion were the most common and severe major symptoms, and headache and fatigue were the most common and severe minor symptoms. Patients received an average of 2.7 antibiotic courses and used nasal steroids and prescription antihistamines 18.3 and 16.3 weeks, respectively, in a 12-month period. Mean medical resource costs were $921 per patient-year. CRS caused an average of 4.8 days of missed work per 12-month period. The overall yearly economic cost of CRS was $1539 per patient.Conclusion: Nasal and facial symptoms prevail over systemic and oropharyngeal symptoms in CRS. Significant medical resource expenditures and global economic costs accompany CRS.