The role of the subfornical organ in drinking induced by angiotensin in the Japanese quail, Coturnix coturnix japonica
The role of the subfornical organ in drinking induced by angiotensin in the Japanese quail, Coturnix coturnix japonica
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穹窿下器官在血管紧张素诱导日本鹌鹑饮水中的作用
DOI：
10.1007/bf00220662
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发表时间：
1977
影响因子：
3.6
通讯作者：
Y. Takei
中科院分区：
文献类型：
--
作者：
Y. Takei
合成5-缬氨酸血管紧张素II（AII）诱导大量饮水时，直接应用于穹窿下器官（SFO）在日本鹌鹑。可靠的响应，获得了低至1纳克的AII。水摄入量呈剂量依赖性增加，从5 ng增加到1 ng。观察到100 ng时的潜伏期为73.0 ± 11.0秒。SFO的电破坏显著减少了静脉内和颅内AII注射引起的水摄入量。该下降与SFO病变的程度成比例。因此，可以想象，SFO在鸟类中AII的饮水诱导中起着重要的作用，正如在哺乳动物中所建议的那样。
Synthetic 5-valine angiotensin II (AII) induced copious drinking when applied directly to the subfornical organ (SFO) in the Japanese quail. Reliable response was obtained with as little as 1 ng of AII. The amount of water intake increased dose-dependently from 5 ng to 1 ng. A latent period of 73.0 ± 11.0 seconds at 100 ng was noted. The electrical destruction of the SFO significantly reduced the amount of water intake induced by both intravenous and intracranial AII injections. The decrease was proportional to the extent of the SFO lesion. It is conceivable, therefore, that the SFO plays an important role in elicitation of drinking by AII in birds as suggested in mammals.