Associations between changes in physical activity and risk factors for coronary heart disease in a community-based sample of men and women: the Stanford Five-City Project.
Associations between changes in physical activity and risk factors for coronary heart disease in a community-based sample of men and women: the Stanford Five-City Project.
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基于社区的男性和女性样本中体力活动变化与冠心病危险因素之间的关联：斯坦福五城项目。
DOI：
10.1093/oxfordjournals.aje.a116849
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发表时间：
1993
影响因子：
5
通讯作者：
Fortmann,SP
中科院分区：
文献类型：
--
作者：
Young,DR;Haskell,WL;Jatulis,DE;Fortmann,SP
涉及志愿者的有氧运动训练研究通常会导致心血管风险因素的改善。然而，在一个更具代表性的样本中，比如一个社区，人们对体力活动变化和风险因素变化之间的关系知之甚少。本研究评估了1979年至1985年斯坦福五城项目队列样本中综合体力活动改变评分与心血管危险因素变化之间的相关性。对年龄在18至74岁之间的男性（n= 380）和女性（n= 427）的自我报告体力活动的变化以及总胆固醇、高密度脂蛋白胆固醇（HDL胆固醇）、收缩压、静息脉搏率和体重指数(体重（kg)/身高(m)2）的变化进行评估。对于男性，综合体力活动评分的改善与高密度脂蛋白胆固醇的增加（r= 0.14,p= 0.005）、体重指数（r= - 0.16,p= 0.001）和估计的10年冠心病风险评分（r= - 0.10,p= 0.056）显著相关。对于女性，体力活动评分的改善与高密度脂蛋白胆固醇（r= 0.11,p= 0.028）和静息脉搏率（r= - 0.15,p= 0.001）的变化有关。这些数据表明，5年以上体力活动的增加与男性和女性主要心血管疾病危险因素的变化呈正相关，并支持在社区范围内促进体力活动的公共健康功效。流行病学杂志1993；138:205-16。
Aerobic exercise training studies involving volunteers generally result in an improved cardiovascular risk factor profile. Little is known, however, about associations between physical activity change and risk factor change in a more representative sample, such as a community. This investigation evaluated correlations between a composite physical activity change score and change in cardiovascular risk factors from 1979 to 1985 in the cohort sample of the Stanford Five-City Project. Men (n= 380) and women (n= 427) between the ages of 18 and 74 years were evaluated for change in self-reported physical activity and change in total cholesterol, high density lipoprotein cholesterol (HDL cholesterol), systolic blood pressure, resting pulse rate, and body mass index (weight (kg)/height (m)2). For men, improvement in the composite physical activity score significantly correlated with an increase in HDL cholesterol (r= 0.14,p= 0.005) and decreases in body mass index (r= −0.16,p= 0.001) and estimated 10-year coronary heart disease risk score (r= −0.10,p= 0.056). For women, improvement in the physical activity score was associated with changes in HDL cholesterol (r= 0.11 ,p= 0.028) and resting pulse rate (r= −0.15,p= 0.001). These data demonstrate that an increase in physical activity over 5 years is favorably associated with changes in major cardiovascular disease risk factors in men and women and support the public hearth efficacy of community-wide promotion of physical activity.Am J Epidemiol1993; 138:205–16.