Theoretical Biology and Medical Modelling Open Access a Model Analysis of Static Stress in the Vestibular Membranes
Theoretical Biology and Medical Modelling Open Access a Model Analysis of Static Stress in the Vestibular Membranes
复制标题
DOI：
--
复制
发表时间：
--
期刊：
影响因子：
--
通讯作者：
D. J. Pender
中科院分区：
文献类型：
--
作者：
D. J. Pender
背景：前庭核心膜结构由连续连接的胞室、壶腹和半规管组成，最早出现在数亿年前的原始鱼类中，并在随后的进化过程中基本保持不变。高等生物的迷宫建立在这个核心结构上，并增加了系统发育上较新的膜结构，即囊、lagena和耳蜗。对这些核心前庭膜的静态应力的分析可能有助于更好地理解应力在长期衍生膜结构演变中的作用，以及在梅尼埃病中所见的短期膜扭曲。
Background: The scheme of the core vestibular membranes, consisting of serially connected utricle, ampulla and semicircular canal, first appeared hundreds of millions of years ago in primitive fish and has remained largely unchanged during the subsequent course of evolution. The labyrinths of higher organisms build on this core structure, with the addition of the phylogenetically newer membrane structures, namely, saccule, lagena and cochlea. An analysis of static stress in these core vestibular membranes may contribute to a better understanding of the role of stress in the evolution of derivative membrane structures over the long term as well as the short-term membrane distortions seen in Meniere's disease.