Maternal control of embryogenesis by medea, a Polycomb group gene in Arabidopsis
Maternal control of embryogenesis by medea, a Polycomb group gene in Arabidopsis
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DOI：
10.1126/science.280.5362.446
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发表时间：
1998-04-17
期刊：
影响因子：
56.9
通讯作者：
Gagliano, WB
中科院分区：
文献类型：
--
作者：
Grossniklaus, U;Vielle-Calzada, JP;Gagliano, WB
配子体母体效应突变体medea（mea）在拟南芥胚胎发生过程中表现出异常的生长调节。来自mea卵的胚在种子干燥过程中过度生长并死亡。胚胎致死率与父本贡献和基因剂量无关。mea表型与亲本冲突理论对亲本起源特异性效应的进化是一致的。MEA编码类似于Zeste增强子的SET结构域蛋白，其是Polycomb组的成员。在动物中，Polycomb组蛋白通过细胞分裂确保表达模式的稳定遗传，并调节细胞增殖的控制。
The gametophytic maternal effect mutant medea (mea) shows aberrant growth regulation during embryogenesis in Arabidopsis thaliana. Embryos derived from mea eggs grow excessively and die during seed desiccation. Embryo lethality is independent of the paternal contribution and gene dosage. The mea phenotype is consistent with the parental conflict theory for the evolution of parent-of-origin-specific effects. MEA encodes a SET domain protein similar to Enhancer of zeste, a member of the Polycomb group. In animals, Polycomb group proteins ensure the stable inheritance of expression patterns through cell division and regulate the control of cell proliferation.