Body height and imipramine side-effects.
Body height and imipramine side-effects.
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DOI：
10.1136/bmj.2.5602.406
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发表时间：
1968-05
影响因子：
--
通讯作者：
A. Porter
中科院分区：
文献类型：
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作者：
A. Porter
讨论 尽管最长随访期只有两年半，但大多数患者满意的生活质量使我们相信尸体肾移植是一种有价值的治疗方法。我们的病人不需要说服力；大多数人患有严重的尿毒症症状，通常并发高血压、心力衰竭、周围神经炎和心包炎。即使最终的预后不确定，从这种垂死的状态恢复到正常的生活也是值得的。透析床的压力和尸体捐献者的短缺导致我们开始实施有限的活体移植计划，其中的活体捐献者来自坚持捐献肾脏的近亲。我们认为，在这种情况下拒绝进行移植是没有道理的，因为替代方案就是死亡。过去两年，由于转诊医院的透析设施不足，等待名单上已有 20 人死亡。然而，在英国每年有 2,000-3,000 名 5 至 55 岁患者死于尿毒症的背景下，这个数字意义不大。不幸的是，目前英国的透析和移植中心只能治疗其中的一小部分病例。
Discussion Though themaximum follow-up period is only two and a half years, the satisfactory quality of life of the majority of our patients has convinced us that cadaveric renal transplanta-tion is valuable therapy. Our patients do not require con-vincing; most had suffered severe symptoms of uraemia often complicated by hypertension, heart failure, peripheral neuritis, and pericarditis. To be restored from such a moribund con-dition to a normal life is worth while even if the ultimate prognosis is uncertain. The pressure on dialysis beds and the shortage of cadaver donors caused us to embark on a limited programme of live donor transplants from close blood relatives who insisted on giving a kidney. We feel that it is unjustifiable to refuse to perform a transplant under these circumstances when the alternative is death. There have been 20 deaths on the waiting-list in the past two years due to inadequate facilities for dialysis in the referring hospitals. This figure, however, means little in the context of the 2,000-3,000 deaths per annum from uraemia in the United Kingdom in patients between the ages of 5 and 55. Unfortunately, at present the dialysis and transplant centres in the United Kingdom can treat only a small fraction of these cases.