Metaanalysis of risk factors for mortality in patients with hip fracture.
Metaanalysis of risk factors for mortality in patients with hip fracture.
复制标题
髋部骨折患者死亡危险因素的荟萃分析。
作者：
Debbie Norring;A. S. Laulund;J. Lauritzen;B. Duus;S. van der Mark;M. Mosfeldt;H. Jørgensen
介绍
本荟萃分析的目的是评估三种不同的临床评分系统与髋部骨折患者死亡率的相关性。
方法
于2011年11月13日使用PubMed和Embase进行了文献检索。检索得到了315篇出版物，根据纳入标准对这些出版物进行了审查。
结果
13项研究被纳入进一步处理。以下临床评分系统被发现对髋部骨折患者的死亡率具有预测价值：美国麻醉医师协会（阿萨）评分为3分或以上（比值比（OR）：3.07; 95%可信区间（CI）：2.78-3.38; p < 0.00001，包括15，625名研究参与者），Charlson Comorbid Index（CCI）评分为1或以上（OR：2.05; 95%CI：1.79-2.34; p < 0.00001，包括13，570名研究参与者）和痴呆（用简易精神状态检查评估或从期刊提取获得）（OR：2.73; 95%CI：1.64-4.57; p = 0.0001;包括1，782名研究参与者）。
结论
目前的荟萃分析表明，阿萨评分，CCI评分和评估既存痴呆是有用的预测髋部骨折患者的死亡率。
INTRODUCTION
The aim of this meta-analysis is to assess the association of three different clinical score systems with the mortality in hip fracture patients.
METHODS
A literature search was conducted on November 13, 2011 using PubMed and Embase. The search yielded 315 publications which were reviewed on the basis of the inclusion criteria.
RESULTS
Thirteen studies were included for further processing. The following clinical score systems were found to be of prognostic value for mortality in hip fracture patients: a high American Society of Anesthesiologists (ASA) score of three or above (odds ratio (OR): 3.07; 95% confidence interval (CI): 2.78-3.38; p < 0.00001, 15,625 study participants included), a Charlson Comorbidity Index (CCI) score of one or more (OR: 2.05; 95% CI: 1.79-2.34; p < 0.00001, 13,570 study participants included) and dementia (assessed with Mini Mental State Examination or obtained from journal extraction) (OR: 2.73; 95% CI: 1.64-4.57; p = 0.0001; 1,782 study participants included).
CONCLUSION
The present meta-analysis showed that the ASA score, the CCI score and assessment of preexisting dementia are useful in predicting the mortality of hip fracture patients.