Size, Neurochemistry, and Segmental Distribution of Sensory Neurons Innervating the Rat Tibia
Size, Neurochemistry, and Segmental Distribution of Sensory Neurons Innervating the Rat Tibia
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DOI：
10.1002/cne.22160
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发表时间：
2009-11-20
影响因子：
2.5
通讯作者：
Ivanusic, Jason J.
中科院分区：
文献类型：
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作者：
Ivanusic, Jason J.
逆行标记已被用来识别支配大鼠胫骨骨膜、髓腔和小梁骨的腰背根神经节(DRG)中的感觉神经元。报告了支配这些骨室的感觉神经元的大小、神经化学特征[异凝素B4(IB4)结合、P物质(SP)、降钙素基因相关肽(CGRP)和NF200免疫反应(-IR)]和节段性分布。在骨膜、髓腔和小梁骨(骨骺)注射快蓝后，在同侧(而不是对侧)腰椎背根神经节中可观察到逆行标记神经元。它们主要是小的(
Retrograde labeling has been used to identify sensory neurons in the lumbar dorsal root ganglia (DRG) that innervate the rat tibial periosteum, medullary cavity, and trabecular bone. The size, neurochemical profile [isolectin B4 (IB4) binding, substance P (SP), calcitonin gene-related peptide (CGRP), and NF200 immunoreactivity (-IR)], and segmental distribution of sensory neurons innervating each of these bony compartments are reported. After injections of fast blue into the periosteum, medullary cavity, and trabecular bone (epiphysis), retrogradely labeled neurons were observed throughout the ipsilateral (but not contralateral) lumbar DRG. They were predominantly small (