Tempo dependence of middle- and long-latency auditory responses: power and phase modulation of the EEG at multiple time-scales
Tempo dependence of middle- and long-latency auditory responses: power and phase modulation of the EEG at multiple time-scales
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DOI：
10.1016/j.clinph.2004.03.024
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发表时间：
2004-08
影响因子：
4.7
通讯作者：
J. Snyder;E. Large
中科院分区：
文献类型：
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作者：
J. Snyder;E. Large
目的我们测量了神经电活动的功率和相位调制对纯音模式听觉反应的影响，纯音模式具有典型的音乐开始间隔。方法以 150 至 3125 毫秒的 10 种不同节奏和随机间隔向 8 名受试者呈现音调。我们根据音调开始前基线和试验中的 TF 相位一致性来量化时频 (TF) 功率。获得中潜伏期听觉反应和长潜伏期听觉反应的峰峰值事件相关电位（ERP）振幅值进行比较。结果长潜伏期反应（LLR）的ERP振幅、功率调制大小和相位相干量在较慢的节奏下较大，但中潜伏期反应（MLR）则不然。多元回归分析表明，对于 MLR 和 LLR，相位调制比功率调制更能预测 ERP 幅度。结论对于中潜伏期和长潜伏期听觉反应，相位调制比功率调制更能预测 ERP 幅度。意义快节奏时 MLR 没有减弱，表明它对于研究音乐和语音模式的早期皮层处理是有用的。
ObjectiveWe measured the influences of power and phase modulations of neuroelectric activity on auditory responses to pure-tone patterns with inter-onset intervals typical of music.MethodsTones were presented to 8 subjects at 10 different tempos from 150 to 3125 ms and with random intervals. We quantified time-frequency (TF) power with respect to a pre-tone-onset baseline and the TF phase coherence across trials. Peak-to-peak event-related potential (ERP) amplitude values for the middle and long-latency auditory responses were obtained for comparison.ResultsERP amplitude, size of power modulation, and amount of phase coherence were larger at slower tempos for the long-latency response (LLR) but not for the middle-latency response (MLR). Multiple regression analysis indicated that for MLR and LLR, phase modulation was a better predictor of ERP amplitude than power modulation.ConclusionsPhase modulation is a better predictor of ERP amplitude than power modulation for middle and long-latency auditory responses.SignificanceLack of diminution of the MLR at fast tempos indicates its usefulness for studying early cortical processing of music and speech patterns.