Cigarette smoking, obesity, diuretic use, and coffee consumption as risk factors for renal cell carcinoma.
Cigarette smoking, obesity, diuretic use, and coffee consumption as risk factors for renal cell carcinoma.
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DOI：
10.1093/jnci/77.2.351
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发表时间：
1986-08
期刊：
影响因子：
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通讯作者：
M. Yu;T. Mack;R. Hanisch;C. Cicioni;B. Henderson
中科院分区：
文献类型：
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作者：
M. Yu;T. Mack;R. Hanisch;C. Cicioni;B. Henderson
对160例55岁以下的肾细胞癌病例和相同数量的年龄（5年内）、种族和性别匹配的社区对照进行了访谈。吸烟是男性肾癌的危险因素[相对危险度(RR) = 2.1，单侧P = 0.02]，而女性则不是（RR = 1.1, P = 0.50）。肥胖是男性和女性的重要风险因素：与10年前的Quetelet指数相比，第4个四分位数的RR为男性2.5，女性3.3。女性的其他危险因素是利尿剂的使用（RR = 4.5, P = 0.002）和每天喝咖啡（RR = 2.3, P = 0.06）。
One hundred sixty incident cases of renal cell carcinoma under the age of 55 years and an equal number of age-(within 5 yr), race-, and sex-matched neighborhood controls were interviewed. Cigarette smoking was a risk factor for renal cell carcinoma in males [relative risk (RR) = 2.1, one-sided P = .02] but not in females (RR = 1.1, P = .50). Obesity was a significant risk factor in both males and females: The RR for a 4th quartile compared to a 1st quartile Quetelet's Index 10 years ago was 2.5 for males and 3.3 for females. Additional risk factors in females were diuretic use (RR = 4.5, P = .002) and daily coffee consumption (RR = 2.3, P = .06).