RFLP in human F13A gene.

RFLP in human F13A gene.
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人类 F13A 基因中的 RFLP。

DOI:
10.1093/nar/18.5.1317
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发表时间:
1990
影响因子:
14.9
通讯作者:
Jagadeeswaran,P
Jagadeeswaran,P
中科院分区:
生物学2区
文献类型:
--
作者:
Jagadeeswaran,P

文献摘要

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Source/Description: Blood coagulation F13A cDNA was isolated by antibody screening of a human placenta cDNA library. The clone extends from the nucleotide position 321 to 3761 corresponding to the cDNA reported by Grundman et al.(1). Polymorphism: EcoRI, HindI, PvuII or BamHI digests ofhuman genomic DNA were probed with the F13A cDNA by Southern blot analysis. The polymorphic bands are indicated by arrow heads as shown in figure.Frequency: Genomic DNA from 18 normal individuals was analysed. EcoRI: 30kb (0.50), 18kb (0.17), 16kb (0.33), 15kb (0.31), 12 kb (0.39). HindIf: 5.0 kb (0.28), 5.2 kb (0.29), 4.0 kb (0.64), 3.8 kb (0.21). PvuII: 10.5 kb (0.44), 8.0 kb (0.33), 7.5 kb (0.22), 6.5 kb (0.50), 6.0 kb (0.66). BamHI: 5.9 kb (0.61), 3.0 kb (0.50).