Effects of strong static magnetic fields on nerve excitation
Effects of strong static magnetic fields on nerve excitation
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DOI：
10.1109/tmag.2006.879822
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发表时间：
2006-10-01
影响因子：
2.1
通讯作者：
Ueno, Shoogo
中科院分区：
文献类型：
--
作者：
Sekino, Masaki;Tatsuoka, Hozumi;Ueno, Shoogo
最近在医疗设备和磁悬浮超导磁体方面的进展使人们认识到磁场的生物效应的重要性。本研究旨在探讨强静磁场对大鼠坐骨神经动作电位的影响。在脚后跟的皮肤下插入一对针状电极，以施加电刺激。在高达8 t的静磁场下，通过连接在神经束上的一对电极测量左坐骨神经的复合动作电位，确定了源自a - α和C纤维的动作电位。暴露在静态磁场中不影响a α动作电位的振幅。静磁场的增加增加了C光纤峰值的振幅。这些结果表明，暴露于强静态磁场增强神经纤维的兴奋，这种效果取决于所涉及的纤维的类型。
Recent advances in superconducting magnets for medical devices and for magnetic levitation have given rise to the importance of understanding the biological effects of magnetic fields. The purpose of this study was to investigate the effects of strong static magnetic fields on the action potentials of the rat sciatic nerve. A pair of needle electrodes was inserted beneath the skin of the heel for applying electrical stimulations. Compound action potentials of the left sciatic nerve were measured from a pair of electrodes attached to the nerve bundle under static magnetic fields of up to 8 T. We identified the action potentials originating from the A alpha and C fibers. The exposure to a static magnetic field did not affect the amplitude of the A alpha action potentials. An increase in the static magnetic field increases the amplitudes of the peaks of the C fiber. These results indicated that exposure to strong static magnetic fields enhances the excitation of nerve fibers, and this effect depends on the type of fibers involved.