Prognostic molecular biomarkers for cutaneous malignant melanoma.

Prognostic molecular biomarkers for cutaneous malignant melanoma.
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皮肤恶性黑色素瘤的预后分子生物标志物。

DOI:
10.1002/jso.21969
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发表时间:
2011
影响因子:
2.5
通讯作者:
Hoon,DaveSB
Hoon,DaveSB
中科院分区:
医学3区
文献类型:
--
作者:
Tanaka,Ryo;Koyanagi,Kazuo;Narita,Norihiko;Kuo,Christine;Hoon,DaveSB

文献摘要

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Molecular signatures of melanoma have propelled new approaches to early diagnosis, monitoring of treatment response, and targeted therapy. This review discusses messenger RNA (mRNA), genomic, and epigenomic melanoma biomarkers in blood and tissue specimens. The major focus is on tissue‐based molecular assays to upstage sentinel lymph nodes (SLNs), and blood‐based assays to detect melanoma progression by monitoring levels of circulating tumor cells (CTC) and circulating DNA. J. Surg. Oncol. 2011; 104:438–446. © 2011 Wiley‐Liss, Inc.