"Off-the-shelf" microfluidic devices for the production of liposomes for drug delivery
"Off-the-shelf" microfluidic devices for the production of liposomes for drug delivery
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DOI：
10.1016/j.msec.2016.03.056
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发表时间：
2016-07-01
影响因子：
7.9
通讯作者：
Nastruzzi, C.
中科院分区：
文献类型：
--
作者：
Bottaro, E.;Nastruzzi, C.
提出了一种“现成的”微流控芯片方法，利用低成本、市售组件来生产脂质体。具有不同几何形状的微流体装置已被方便地设计和组装，从而可以生产窄分散的单层且非常可重复的脂质体。所提出的结果表明，现成的微流体装置对于有效制备用于生物医学应用的不同脂质基胶体系统具有很大的前景。 (C) 2016 Elsevier B.V. 保留所有权利。
An "off-the-shelf" microfluidic chip approach, utilizing lowcost, commercially available components, for liposome production, is presented. Microfluidic devices with different geometries have been conveniently designed and assembled, allowing the production of narrowly dispersed unilamellar and very reproducible liposomes. The presented results indicate that off-the-shelf microfluidic devices can hold great promises for the efficient preparation of different lipid based colloidal systems for biomedical applications. (C) 2016 Elsevier B.V. All rights reserved.