The Wernicke-Korsakoff syndrome.
The Wernicke-Korsakoff syndrome.
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韦尼克-科萨科夫综合症。
DOI：
10.4135/9781483365817.n1486
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发表时间：
1980
影响因子：
4
通讯作者：
Feinberg Jf
中科院分区：
文献类型：
--
作者：
Feinberg Jf
韦尼克脑病和科萨科夫精神病代表了同一病理过程的连续体。病因是硫胺素的绝对缺乏，而不是酒精的直接毒性作用。韦尼克脑病的三联症--全面性混乱状态、眼肌麻痹和眼球震颤以及共济失调--偶尔出现在慢性酒精中毒患者身上，通常通过立即接受硫胺素治疗而减弱。科萨科夫精神病的三重症状--记忆力丧失、学习障碍和说话--既可以在急性护理环境中看到，也可以在长期护理环境中看到。
Wernicke's encephalopathy and Korsakoff's psychosis represent a continuum of the same pathologic process. The etiology is an absolute deficiency of thiamine rather than a direct toxic effect of alcohol. The triad of Wernicke's encephalopathy--global confusional state, ophthalmoplegia and nystagmus, and ataxia--is occasionally seen in chronic alcoholics and is often attenuated by immediate thiamine treatment. The triad of Korsakoff's psychosis--memory loss, learning deficits and confabulation--may be seen in either the acute or the long-term care setting.