Sleep Duration and Hypertension: Analysis of >700,000 Adults by Age and Sex
Sleep Duration and Hypertension: Analysis of >700,000 Adults by Age and Sex
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DOI：
10.5664/jcsm.7176
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发表时间：
2018-01-01
影响因子：
4.3
通讯作者：
Morgenthaler, Timothy I.
中科院分区：
文献类型：
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作者：
Grandner, Michael;Mullington, Janet M.;Morgenthaler, Timothy I.
研究目的：本研究的目的是在一个跨度为10年的具有全国代表性的大型数据集中评估睡眠时间与高血压之间的横断面关系。这项分析可以提供关于睡眠时间与高血压之间关系的详细信息，以及不同人口群体之间的差异。方法：数据来自2013年行为风险因素监测系统（n = 433,386）和2007-2016年全国健康访谈调查（n = 295,331）。这些数据是由疾病控制和预防中心从具有全国代表性的样本中收集的。将调查合并，并在所有分析中使用调查特定权重。在两项调查中，睡眠时间都是通过“平均来说，你在24小时内睡了多少小时？”这一项来评估的。高血压以自述病史评估。两个数据集中的协变量评估相同，包括年龄（5年分组）、性别、种族/民族和就业状况。结果：在校正分析中，与睡眠7小时的人相比，睡眠10小时的人高血压的风险增加（OR = 1.41, P < .0005）。当按年龄、性别和种族/民族分组分层时，短睡眠与70岁以下所有年龄组的风险增加有关，长睡眠（>=仅10小时）与24岁以下和74岁以下的所有年龄组的风险增加有关。虽然长时间睡眠的发现在黑人/非裔美国人和其他/多种族群体中不那么明显，但在所有种族/民族中，短时间睡眠的发现相对一致。3-way睡眠x年龄x性别的显著交互作用（P < .0005）表明这种关系取决于年龄和性别。对于男性和女性来说，随着年龄的增长，睡眠不足与高血压的相关性会降低，但对于女性来说，在整个成年期，睡眠不足与高血压之间的相关性更高。结论：在大多数年龄组中，睡眠时间长短都与高血压风险增加有关。协变量对长时间睡眠关系的影响更大。年轻人和女性与睡眠不足的关系更强。
Study Objectives: The objective of this study was to evaluate the cross-sectional relationship between sleep duration and hypertension in a large, nationally-representative dataset that spans 10 years. This analysis may provide detailed information with high resolution about how sleep duration is related to hypertension and how this differs by demographic group.Methods: Data were aggregated from the 2013 Behavioral Risk Factor Surveillance System (n = 433,386) and the combined 2007-2016 National Health Interview Surveys (n = 295,331). These data were collected by the Centers for Disease Control and Prevention from nationally-representative samples. Surveys were combined, and survey-specific weights were used in all analyses. Sleep duration was assessed with the item, "On average, how many hours of sleep do you get in a 24-hour period?" in both surveys. Hypertension was assessed as self-reported history. Covariates were assessed identically in both datasets and included, age (in 5-year groupings), sex, race/ethnicity, and employment status.Results: In adjusted analyses, compared to 7 hours, increased risk of hypertension was seen among those sleeping = 10 hours (OR = 1.41, P < .0005). When stratified by age, sex, and race/ethnicity groups, short sleep was associated with increased risk for all age groups < 70 years, and long sleep (>= 10 hours only) was associated with risk for all except < 24 years and > 74 years. Findings for short sleep were relatively consistent across all race/ethnicities, although findings for long sleep were less pronounced among Black/African-American and Other/Multiracial groups. A significant sleep by 3-way sleep x age x sex interaction (P < .0005) suggests that the relationship depends on both age and sex. For both men and women, the OR of having hypertension associated with short sleep decreases with increasing age, but there is a higher association between short sleep and hypertension for women, throughout the adult lifespan.Conclusions: Both short and long sleep duration are associated with increased hypertension risk across most age groups. The influence of covariates is stronger upon long sleep relationships. Relationships with short sleep were stronger among younger adults and women.