Tinnitus Is Associated With Extended High-frequency Hearing Loss and Hidden High-frequency Damage in Young Patients.
Tinnitus Is Associated With Extended High-frequency Hearing Loss and Hidden High-frequency Damage in Young Patients.
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耳鸣与年轻患者的长期高频听力损失和隐藏的高频损伤有关
DOI：
10.1097/mao.0000000000002983
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发表时间：
2021-03-01
期刊：
影响因子：
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通讯作者：
Li H
中科院分区：
文献类型：
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作者：
Song Z;Wu Y;Tang D;Lu X;Qiao L;Wang J;Li H
目的：分析传统纯音测听（PTA）反应正常的年轻耳鸣患者的扩展高频（EHF）和高频听力测试结果，探讨耳鸣与听力损失（HL）之间的相关性。研究设计：病例对照研究。地点：中国三级眼耳鼻喉科医院。研究对象：年龄18~35岁、常规PTA（125Hz~8kHz）正常的耳鸣患者纳入耳鸣组。将同龄无耳鸣志愿者纳入对照组。主要指标：比较所有参与者的EHF-HL发生率和各频率的听阈，以及最大HL频率和边缘频率的分布。结果：共纳入耳鸣组28例（43耳），对照组34例（68耳）。耳鸣组EHF-HL的发生率、4~16kHz各频率的平均听阈、最大听阈均显着升高。耳鸣组的边缘频率低于对照组（10.4±3.1kHz vs 12.3±2.5kHz，p=0.010）。 EHF受损者的主导耳鸣音高与耳鸣听力级响度呈正相关（r = 0.627，p < 0.001）。结论：常规PTA中耳鸣听力正常的患者更容易表现出EHF-HL征象和高频隐性损害。建议进行极高频听力测试和高频听力测试的后续测试，以便及早发现听力障碍并及时干预。
Objectives: To analyze the results of extended high-frequency (EHF) and high-frequency hearing tests in young patients with tinnitus who show normal response in conventional pure-tone audiometry (PTA), and to explore the correlation between tinnitus and hearing loss (HL). Study Design: A case–control study. Setting: A Tertiary Eye Ear Nose & Throat Hospital of China. Participants: Patients with tinnitus, aged 18 to 35 years old, and with normal conventional PTA (125 Hz–8 kHz) were enrolled in the tinnitus group. Volunteers without tinnitus of the same age were enrolled in the control group. Main Outcome Measures: The incidence of EHF-HL and the hearing thresholds at each frequency, as well as the distribution of maximum HL frequency and edge frequency in all participants were compared. Results: In total, 28 cases (43 ears) were enrolled in the tinnitus group and 34 cases (68 ears) in the control group. The incidence of EHF-HL, average hearing threshold of each frequency ranging from 4 to 16 kHz, and the maximum hearing threshold were significantly higher in the tinnitus group. The edge frequency in the tinnitus group was lower than that in the control group (10.4 ± 3.1 kHz versus 12.3 ± 2.5 kHz, p = 0.010). The dominant tinnitus pitch in cases whose EHF was impaired was positively correlated with the hearing-level loudness of tinnitus (r = 0.627, p < 0.001). Conclusion: Patients with tinnitus and normal hearing in conventional PTA showed signs of EHF-HL and hidden damage in the high-frequencies more easily. EHF hearing tests and the follow-up of HF hearing tests are recommended to facilitate early detection of hearing impairment for timely intervention.