ECDC/EFSA/EMA second joint report on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals: Joint Interagency Antimicrobial Consumption and Resistance Analysis (JIACRA) Report

ECDC/EFSA/EMA second joint report on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals: Joint Interagency Antimicrobial Consumption and Resistance Analysis (JIACRA) Report
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DOI:
10.2903/j.efsa.2017.4872
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发表时间:
2017-07-01
期刊:
影响因子:
3.3
通讯作者:
--
中科院分区:
农林科学3区
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--
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第二份ECDC/EFSA/EMA关于人类和食用动物细菌中抗菌药物消耗量(AMC)和抗菌药物耐药性(AMR)综合分析的联合报告解决了2013-2015年各机构在欧盟范围内监测网络获得的数据。在国家和欧洲一级比较了这两个部门的AMC,以mg/kg估计生物量表示。在这两个部门,各国之间的差异很大。首次使用了猪和家禽AMC的估计数据。应用单因素和多因素分析研究AMC与AMR之间的关系。2014年,动物的平均AMC(152 mg/kg)高于人类(124 mg/kg),但AMC中位数则相反(分别为67和118 mg/kg)。在28个国家中,有18个国家的动物AMC低于人类。单因素分析显示,
The second ECDC/EFSA/EMA joint report on the integrated analysis of antimicrobial consumption (AMC) and antimicrobial resistance (AMR) in bacteria from humans and food-producing animals addressed dataobtained by the Agencies' EU-wide surveillance networks for 2013-2015. AMC in both sectors, expressed in mg/kg of estimated biomass, were compared at country and European level. Substantial variations between countries were observed in both sectors. Estimated data on AMC for pigs and poultry were used for the first time. Univariate and multivariate analyses were applied to study associations between AMCand AMR. In 2014, the average AMC was higher in animals (152mg/kg) than in humans (124mg/kg), but the opposite applied to the median AMC (67 and 118mg/kg, respectively). In 18 of 28 countries, AMC was lower in animals than in humans. Univariate analysis showed statistically-significant (p