THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN - THEORY, PROCEDURE AND NORMAL VALUES
THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN - THEORY, PROCEDURE AND NORMAL VALUES
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DOI：
10.1172/jci101994
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发表时间：
1948-01-01
影响因子：
15.9
通讯作者：
SCHMIDT, CF
中科院分区：
文献类型：
--
作者：
KETY, SS;SCHMIDT, CF
本文介绍了一氧化二氮法测定非麻醉状态下人的脑血流量，并对其误差进行了估计。该方法所依据的基本假设已受到exptl。验证一氧化二氮技术和直接测量流量的气泡流量计在猴子之间的比较表明，这两种方法之间的良好协议。在一组正常年轻男性中，脑血流量的平均值为54（[sigma][正负] 12）cc/100 g。/脑O2消耗的平均值为3.3（[σ][±] 0.4）cc。O2/100 g./分钟[long破折号]。
The nitrous oxide method for measurement of cerebral blood flow in unanesthe-tized man is described and its errors estimated. The fundamental assumptions on which the method is based have been subjected to exptl. verification. Comparison between the nitrous oxide technique and direct measurement of flow by means of the bubble flowmeter in monkeys shows excellent agreement between the two methods. In a group of normal young men the mean value for cerebral blood flow was 54 ([sigma][plus or minus] 12) cc/100 g./min. The mean value for cerebral 02 consumption was 3.3 ([sigma][plus or minus] 0.4) cc. O2/100 g./ min.[long dash].