Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin:: Case report

Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin:: Case report
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DOI:
10.1086/318698
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发表时间:
2001-02-15
影响因子:
11.8
通讯作者:
Iseman, MD
Iseman, MD
中科院分区:
医学1区
文献类型:
--
作者:
Berning, SE;Cherry, TA;Iseman, MD

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我们报告的情况下,一个25岁的艾滋病毒阴性的男子与播散性耐多药结核病(MDRTB),谁的复治方案经历了结核病粟粒性疾病的总决议,但进行性结核性脑膜炎。因此,鞘内注射阿米卡星和左氧氟沙星治疗,取得了成功的临床和微生物学结果。
We report the case of a 25-year-old HIV-negative man with disseminated multidrug-resistant tuberculosis (MDRTB), who-on a retreatment regimen-experienced total resolution of TB miliary disease, but progressive TB meningitis. Therefore, intrathecal treatment with amikacin and levofloxacin was instituted, with successful clinical and microbiological results.