The atopic march: The pattern of allergic disease development in childhood
The atopic march: The pattern of allergic disease development in childhood
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DOI：
10.1016/j.iac.2005.02.004
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发表时间：
2005-05-01
影响因子：
2.6
通讯作者：
Bacharier, LB
中科院分区：
文献类型：
--
作者：
Hahn, EL;Bacharier, LB
儿童早期过敏性疾病表现的顺序发展通常被称为特应性进行曲。各种流行病学和出生队列研究已经开始阐明过敏性疾病表现的演变，并确定疾病的风险人群。这些研究，沿着干预研究，强调环境因素和遗传易感性对特应性进行的影响。本文讨论了人群中的特应性疾病的发展风险和干预措施，已被探索，试图修改过敏性疾病的进展。
The sequential development of allergic disease manifestations during early childhood is often referred to as the atopic march. Various epidemiologic and birth-cohort studies have begun to elucidate the evolution of allergic disease manifestations and to identify populations at risk for disease. These studies, along with intervention studies, emphasize the effects of environmental factors and genetic predisposition on the atopic march. This article discusses the populations at risk for the development of atopic conditions and the interventions that have been explored in attempts to modify the progression of allergic disease.