Factors associated with antiretroviral adherence among HIV-infected women with children

Factors associated with antiretroviral adherence among HIV-infected women with children
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DOI:
10.1300/j013v36n01_07
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发表时间:
2002-01-01
期刊:
影响因子:
1.6
通讯作者:
Hoffman, D
Hoffman, D
中科院分区:
医学4区
文献类型:
--
作者:
Murphy, DA;Greenwell, L;Hoffman, D

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招募有HIV症状或AIDS诊断的有年幼健康子女的妇女进行研究,调查她们对抗逆转录病毒药物的依从性(N = 46)。发现依从性非常差,范围从43%(药丸计数评估)到56%(自我报告的3天剂量依从性)。有几个因素与不依从性相关,包括饮酒、感知压力、有伴侣和最小孩子的年龄、坚持治疗的自我效能差以及对遵循治疗方案的益处的预期结果差。迫切需要采取干预措施,帮助这些妇女提高依从性。(C)出版社:The Haworth Press,Inc. All rights reserved.
HIV symptomatic or AIDS diagnosed women who had a young well child were recruited for a study investigating their adherence to antiretrovirals (N = 46). Very poor rates of adherence were found, ranging from 43% (pill count assessment) to 56% (self-report of 3-day adherence to dose). Several factors were associated with nonadherence, including alcohol use, perceived stress, having a partner and age of youngest child, poor self-efficacy to stay with treatment, and poor outcome expectancies regarding the benefits of following the treatment regimen. Interventions to assist these women in improving adherence are urgently needed. (C) 2002 by The Haworth Press, Inc. All rights reserved.