Association between metabolic syndrome and recurrence of nonmuscle-invasive bladder cancer in older adults

Association between metabolic syndrome and recurrence of nonmuscle-invasive bladder cancer in older adults
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DOI:
10.1016/j.urolonc.2020.04.010
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发表时间:
2020-09-01
影响因子:
2.7
通讯作者:
Kirchner, H. Lester
Kirchner, H. Lester
中科院分区:
医学3区
文献类型:
--
作者:
Garg, Tullika;Young, Amanda J.;Kirchner, H. Lester

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背景资料:非肌肉浸润性膀胱癌(NMIBC)不成比例地影响老年人,他们通常患有代谢综合征(MetS)等并存的慢性疾病。尽管先前的研究表明MetS是NMIBC的一个危险因素,但关于MetS是否与NMIBC复发相关的数据有限。我们的目的是评估MetS与接受NMIBC治疗的老年人复发之间的关系。方法:我们确定了1,485名老年(年龄>= 60岁)NMIBC患者(美国癌症分期联合委员会
Background: Nonmuscle-invasive bladder cancer (NMIBC) disproportionately affects older adults who often have coexisting chronic conditions such as metabolic syndrome (MetS). Although prior research suggests that MetS is a risk factor for NMIBC, limited data exists on whether MetS is associated with NMIBC recurrence. Our objective was to evaluate the association between MetS and recurrence in older adults treated for NMIBC.Methods: We identified 1,485 older (age >= 60 years) NMIBC patients (American Joint Committee on Cancer Stage