Left ventricle myocardial performance index derived either by conventional method or mitral annulus tissue-Doppler: A comparison study in healthy subjects and subjects with heart failure
Left ventricle myocardial performance index derived either by conventional method or mitral annulus tissue-Doppler: A comparison study in healthy subjects and subjects with heart failure
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DOI：
10.1016/j.echo.2005.06.006
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发表时间：
2005-12-01
影响因子：
6.5
通讯作者：
Ziacchi, V
中科院分区：
文献类型：
--
作者：
Gaibazzi, N;Petrucci, N;Ziacchi, V
目标.本研究的目的是探讨心肌工作指数（MPI）的临床协议之间的常规测量和。通过二尖瓣环的脉冲波组织多普勒（PW-TD），并测试PW-TD MPI是否可以准确区分健康受试者和。背景：使用PW-TD计算MPI可能比传统的左心室流入/流出道脉冲波多普勒（PWD）方法具有优势;例如，PW-TD MPI计算所需的所有数据可以从单个心动周期导出，而PWD至少需要两个不同的周期。因此，心率变异性不干扰PW-TD MPI。方法和结果。在A组中，我们纳入了70名健康成人，左心室射血分数正常，正常的肌酐，而对于第1组，我们研究了50名CHF患者，左心室射血分数在35%和45%之间。在A组（0.33 +/- 0.09 vs 0.42 +/- 0.09）和1组（0.69 +/- 0.15 vs 0.79 +/- 0.12）中，PWD测量的MPI与PW-TD测量的MPI存在统计学差异（P <0.0001）。尽管如此，在单一受试者中，两种方法之间存在临床一致性。受试者工作特征曲线显示了非常高的准确性，这两种方法来区分CHF患者从健康受试者，最佳截止点是不同的，具体到每种方法：0.50为传统的方法和0.60为PW-TD method.Conclusion：我们发现MPI之间的临床协议在同一主题与传统的PWD方法和PW-TD测量。这两种方法有同样高的诊断准确性CHF，但这项研究支持使用一个更高的MPI临界点最好的诊断准确性时，使用新的PW-TD方法。摘要：我们进行了一项研究，在健康成人和充血性心力衰竭患者调查MPI测量常规和PW-TD的二尖瓣环之间的临床协议。我们发现用常规方法和PWTD测量的MPI之间存在轻微的一致性。两种方法对CHF均有较高的诊断准确率。PW-TD方法要求更高的MPI临界点以获得最佳诊断准确性。
Objectives. The aims of this study were to investigate the clinical agreement between myocardial performance index (MPI) measured conventionally and. by pulsed-wave tissue Doppler (PW-TD) of the mitral annulus, and to test whether PW-TD MPI can accurately differentiate between healthy subjects and. patients affected by congestive heart failure (CHF) with mild to moderate reduction of systolic, function.Background: Calculation of MPI using PW-TD may have advantages over conventional left ventricle inflow/outflow tract pulsed-wave Doppler (PWD) method; for example, all of the data needed for PW-TD MPI calculation can be derived from one single cardiac cycle, whereas with PWD at least two different cycles are needed. Thus, heart rate variability does not interfere with PW-TD MPI.Methods and Results. In group A, we included 70 healthy adults with normal left ventricular ejection fraction and normal diastole, whereas for group 1, we studied 50 patients with CHF and left ventricular ejection fraction between 35% and 45%. MPI measured with PWD was statistically different (P < .0001) from MPI measured with PW-TD both in group A (0.33 +/- 0.09 vs 0.42 +/- 0.09) and group 1; (0.69 +/- 0.15 vs 0.79 +/- 0.12). Nonetheless, clinical agreement existed between the two methods in the single subject. Receiver operating characteristic curves showed very high accuracy for both methods to discriminate patients with CHF from healthy subjects; the optimal cutoff point was different and specific to each method: 0.50 for the conventional method and 0.60 for the PW-TD method.Conclusion: We found clinical agreement between MPI measured in the same subject with the conventional PWD method and with PW-TD. Both methods had similarly high diagnostic accuracy for CHF, but this study supports the use of a higher MPI cut-point for best diagnostic accuracy when using the new PW-TD method.Summary: We performed a study in healthy adults and in patients with congestive heart failure to investigate the clinical agreement between MPI measured conventionally and by PW-TD of the mitral annulus. We found mild agreement between MPI measured by the conventional method and by PWTD. Both methods had high diagnostic accuracy for CHF. PW-TD method requires a higher MPI cut-point for best diagnostic accuracy.