Strain and shear wave ultrasound elastography in evaluation of chronic inflammatory disorders of major salivary glands
Strain and shear wave ultrasound elastography in evaluation of chronic inflammatory disorders of major salivary glands
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DOI：
10.1259/dmfr.20190225
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发表时间：
2020-01-01
影响因子：
3.3
通讯作者：
Mohamed, Maha Eshaq Amer
中科院分区：
文献类型：
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作者：
Elbeblawy, Yasmein Maher;Mohamed, Maha Eshaq Amer
目的：本研究的目的是评估慢性炎症状态的大涎腺超声弹性成像。方法：21例慢性炎症状态的大涎腺和21名健康成人志愿者纳入本研究。所有参与者均接受B型超声和超声弹性成像。应变比和剪切波速度的诊断性能进行了评价的敏感性和特异性在最佳的截止点和接收器工作特征curved.Results下的面积：病例显示腮腺和下颌下腺的中位应变比高于对照组（P值= 0.001），具有统计学意义。所有病例的中位评分在统计学上显著高于对照组（p值< 0.001）。在截断值为1.13时，诊断准确性、敏感性和特异性分别为97.6%、95.2%和100%，AUROC为0.954，可信区间为0.840-0.995。病例显示腮腺的中位剪切波速度高于对照组，具有统计学意义（p值= 0.022），两组的颌下腺无统计学意义差异（p值= 0.216）。所有病例的中位评分在统计学上显著高于对照组（p值< 0.001）。在AUROC = 0.819，置信区间为0.669- 0.920时，诊断准确率为78.6%，敏感性为81%，特异性为76.2%。结论：弹性成像对大涎腺慢性炎症的诊断具有潜在的价值。这一结论还需要进一步的大样本研究来验证。
Objective: The aim of this study was to assess chronic inflammatory conditions of major salivary glands by ultrasound elastography.Methods: 21 patients with chronic inflammatory conditions of major salivary glands and 21 healthy adult volunteers were included in this study. All participants underwent B-mode sonography and ultrasound elastography. The diagnostic performance of strain ratio and shear wave velocity was evaluated by sensitivity and specificity at the optimum cutoff point and the area under the receiver operating characteristic curve.Results: Cases showed statistically significant higher median strain ratio of parotid and submandibular gland than control group (p-value = 0.001). Total cases showed statistically significant higher median scores than control group (p-value < 0.001). At cut-off value of (1.13); diagnostic accuracy, sensitivity and specificity were 97.6, 95.2 and 100% respectively with AUROC 0.954 and confidence interval: 0.840-0.995. Cases showed statistically significant higher median shear wave velocity of parotid gland than control group (p-value = 0.022), with no statistically significant difference in submandibular gland in the two groups (p-value = 0.216). Total cases showed statistically significant higher median scores than control group (p-value < 0.001). At cut-off value of (23.5), diagnostic accuracy was 78.6% with a sensitivity of 81% and specificity of 76.2% with 0.819 AUROC and onfidence interval :0.669-0.920.Conclusion: Our initial experience suggests that elastography may be potentially useful for diagnosis of chronic inflammatory conditions of the major salivary glands. This conclusion needs to be further validated large sample studies.