Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjects
Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjects
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DOI：
10.1016/s0165-1781(98)00040-7
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发表时间：
1998-07-13
影响因子：
11.3
通讯作者：
Moeller, FG
中科院分区：
文献类型：
--
作者：
Dougherty, DM;Steinberg, JL;Moeller, FG
在一项探索性研究中，10名精神分裂症患者和10名正常对照者进行了即时和延迟记忆任务，这是以前开发的连续性能测试的变体。这两项任务都要求参与者识别重复的五位数。数字以500 ms为一系列，并以500 ms的超时间隔。在即时记忆任务中，如果一个数字是相同的，立即在它之前的一个。延迟记忆任务与第一个任务的不同之处在于，刺激之间引入了更长的延迟（3.5秒），并在此延迟期间出现干扰刺激。虽然正常对照组的受试者准确地执行这两项任务（超过80%的正确检测），精神分裂症患者表现不佳，表现更差的延迟记忆任务比即时记忆任务。在即时记忆任务中，两组之间的委托错误率（对相似但不相同的数字做出的反应）几乎相等，但在延迟记忆任务中，正常对照组的委托错误相对较多，而精神分裂症患者的委托错误较少。在受试者组或任务之间未观察到反应延迟的差异。这种模式可能被证明是有用的，在精神病人群和正常对照组之间的即时和延迟记忆能力的细微差异的歧视。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
In an exploratory study, 10 schizophrenic patients and 10 normal control subjects performed immediate and delayed memory tasks, which were variants of previously developed continuous performance tests. Both tasks required participants to identify five-digit numbers which were repeated. Numbers were presented in series for 500 ms each and separated by a 500-ms time-out period. In the immediate memory task, subjects were to respond if a number was identical to the one that had immediately preceded it. The delayed memory task differed from the first task in that a longer delay (3.5 s) between stimuli was introduced, and during this delay distracter stimuli appeared. While normal control subjects performed accurately on both tasks (exceeding 80% correct detections), schizophrenic patients performed poorly, performing worse on the delayed memory task than on the immediate memory task. Rates of commission errors (responses made to similar, but not identical numbers) were nearly equal between groups on the immediate memory task, but on the delayed memory task normal control subjects made relatively more commission errors while schizophrenic patients made fewer commission errors. No differences in response latencies were observed between subject groups or tasks. This paradigm may prove useful in discriminating subtle differences in immediate and delayed memory capability among psychiatric populations and normal control subjects. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.