A conical assembly of six plasma jets for biomedical applications

A conical assembly of six plasma jets for biomedical applications
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DOI:
10.1063/5.0104481
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发表时间:
2022-08
影响因子:
4
通讯作者:
B. Ghimire;E. Szili;R. Short
B. Ghimire;E. Szili;R. Short
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
B. Ghimire;E. Szili;R. Short

文献摘要

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提出了一种用于生物医学应用的由六个排列成矩形图案的等离子射流组成的圆锥形组件。圆锥形结构增加了组件内各个管之间的间隔距离,从而减少了各个等离子射流之间的干扰,并使这些射流能够在输出端汇聚,与并联运行的等离子射流阵列相比,便于进行更均匀的处理。使用等离子体放电的电气和光学诊断以及在去离子水中测量过氧化氢和[公式:参见文本]来表征该设备在生物医学应用中的潜在适用性。特别是,研究发现,通过六个等离子射流的圆锥形组装生产过氧化氢(一种重要的细菌消毒剂)的效率比单一等离子射流的效率高出九倍以上,并且可以在低于300K的生物兼容温度下实现这一点。因此,该设备可用于生物医学应用,特别是在需要更大面积的治疗时,例如某些伤口和癌症肿瘤,其面积可达数十平方厘米。
A conical assembly of six plasma jets arranged in a rectangular pattern for biomedical applications is presented. The conical configuration increases the separation distance between individual tubes within the assembly that reduces interference between individual plasma jets and enables the jets to converge at the output, facilitating more uniform treatment as opposed to plasma jet arrays operated in parallel. Electrical and optical diagnostics of the plasma discharges and measurements of H2O2 and [Formula: see text] production in de-ionized water are used to characterize the potential suitability of the device for biomedical applications. Particularly, it was found that the efficiency in H2O2 (an important bacterial disinfection agent) production by the conical assembly of six plasma jets was more than nine-fold higher compared to its single plasma jet counterpart and that this could be achieved at a biocompatible temperature of below 300 K. Therefore, the device may find use in biomedical applications, particularly where larger area treatments are required such as for certain wounds and cancer tumors that can span areas of tens of cm2.