Making a vertebrate limb: new players enter from the wings
Making a vertebrate limb: new players enter from the wings
复制标题
DOI：
10.1002/bies.1126
复制
发表时间：
2001-10-01
期刊：
影响因子：
4
通讯作者：
Martin, G
中科院分区：
文献类型：
--
作者：
Martin, G
是什么启动了脊椎动物肢体的发育，并诱导它们在那里形成肢体？几年来，这个有趣问题的答案已经被构建在一个工作模型中，即肢体诱导取决于细胞间信号分子成纤维细胞生长因子（FGF）家族的两个成员FGF8和FGF10之间的对话。现在，最近的一篇论文将WNT基因编码的信号的作用写入了脚本中，WNT基因是果蝇无翅基因的脊椎动物亲属。((1))（C）2001年约翰威利父子公司
What initiates vertebrate limb development and induces limbs to form where they do? For several years the answer to this intriguing question has been framed in terms of a working model that limb induction depends on a dialogue between two members of the Fibroblast Growth Factor (FGF) family of intercellular signaling molecules, FGF8 and FGF10. Now, a recent paper has written roles for signals encoded by WNT genes, the vertebrate relatives of the Drosophila wingless gene, into the script.((1)) (C) 2001 John Wiley & Sons, Inc.