Ag2S nanocrystallites deposited over polyamidoamine grafted carbon nanotubes: An efficient NIR active photothermal agent.
Ag2S nanocrystallites deposited over polyamidoamine grafted carbon nanotubes: An efficient NIR active photothermal agent.
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DOI：
10.1016/j.matchemphys.2019.05.040
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发表时间：
2019-08
影响因子：
4.6
通讯作者：
G. Neelgund;Makobi C. Okolie;F. Williams;A. Oki
中科院分区：
文献类型：
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作者：
G. Neelgund;Makobi C. Okolie;F. Williams;A. Oki
通过将聚酰胺胺 (PAMAM) 共价接枝到碳纳米管 (CNT) 上，然后沉积 Ag2S 纳米微晶，合成了一种新型 NIR（近红外）活性光热剂 CNTs-PAMAM-Ag2S。通过在紫外-可见-近红外区域测量的电子吸收光谱初步评估了 CNTs-PAMAM-Ag2S 作为近红外活性光热剂的潜力。 CNTs-PAMAM-Ag2S表现出优异的光热效应，在980nm激光照射下光热转换效率高达26%，效率高于流行的金基和铜基光热剂。 CNTs-PAMAM-Ag2S在1g/mL浓度下测量其光热效应时达到的温度为64.7℃，远远超过癌细胞的温度耐受水平。从而使CNTs-PAMAM-Ag2S能够有效地破坏癌细胞。此外，还发现CNTs-PAMAM-Ag2S的光热效应与其浓度呈线性相关。 CNTs-PAMAM-Ag2S 具有优异的抗光漂白和光腐蚀稳定性。考虑到其出色的光热效应和光热转换效率，CNTs-PAMAM-Ag2S可能成为未来光热治疗中很有前途的光热剂。
A novel NIR (near infrared) active photothermal agent, CNTs-PAMAM-Ag2S has been synthesized by covalent grafting of polyamidoamine (PAMAM) to carbon nanotubes (CNTs) and subsequent deposition of Ag2S nanocrystallites. The potential of CNTs-PAMAM-Ag2S as a NIR active photothermal agent was preliminarily accessed by its electronic absorption spectrum measured in UV–vis–NIR region. The CNTs-PAMAM-Ag2S exhibited excellent photothermal effect and photothermal conversion efficiency of 26% under illumination with 980 nm laser, the efficiency was found to be higher than popular gold and copper based photothermal agents. Temperature attained by CNTs-PAMAM-Ag2S during measurement of its photothermal effect was 64.7 °C at 1 g/mL, which far exceeds the temperature tolerance level of cancer cells. So that CNTs-PAMAM-Ag2S could destroy the cancer cells in an effective manner. Furthermore, it was found the linear dependence of photothermal effect of CNTs-PAMAM-Ag2S over its concentration. CNTs-PAMAM-Ag2S possessed excellent stability against photo-bleaching and photo-corrosiveness. In consideration of its outstanding photothermal effect and photothermal conversion efficiency, CNTs-PAMAM-Ag2S could be a promising photothermal agent to employ in future photothermal therapy.