One-step modification of nano-hydroxyapatite coating on titanium surface by hydrothermal method
One-step modification of nano-hydroxyapatite coating on titanium surface by hydrothermal method
复制标题
水热法一步法修饰钛表面纳米羟基磷灰石涂层
DOI：
10.1016/j.surfcoat.2010.08.088
复制
发表时间：
2010-12-25
影响因子：
5.4
通讯作者：
Wei, Shicheng
中科院分区：
文献类型：
--
作者：
Hu, Xixue;Shen, Hong;Wei, Shicheng
由于用于骨科和牙科植入物的金属生物材料缺乏反应性官能团，因此这些材料的生物活性改性具有挑战性。为了提高骨传导性，喷砂和酸蚀的钛（SIA-Ti）盘在羟基磷灰石（HA）的简单悬浮液中通过一步法进行水热处理。采用X射线光电子能谱（XPS）、扫描电子显微镜（SEM）、傅立叶变换红外光谱（FTIR）和X射线粉末衍射（XRD）等分析手段，研究了纳米HA的表面化学、表面形貌和结构变化。结果表明，水热处理后，钛表面羟基浓度增加，水热处理温度和时间的提高，钛表面形成纳米羟基磷灰石的能力增强。通过超声清洗工艺检测，所形成的纳米HA涂层的结合强度高于HA悬浮沉积直接生成的HA涂层的结合强度。体外培养的MC 3 T3-E1细胞在SLA-Ti和HT-Ti盘上显示，HT-Ti比SIA-Ti更有利于细胞的附着和分化。因此，一步水热处理HA悬浮液是一种简单、有效和有前途的钛种植体HA涂层改性方法。(C)2010爱思唯尔有限公司版权所有。
Since metallic biomaterials used for orthopedic and dental implants possess a paucity of reactive functional groups, bioactivity modification of these materials is challenging. To enhance osteoconductivity, sandblasted and acid etched titanium (SIA-Ti) discs were hydrothermally treated in simple suspension of hydroxyapatite (HA) by a one-step method in the present work. Change of surface chemistry, surface morphology of samples, and structure of formed nano-HA were investigated by X-ray photoelectron spectrometry (XPS), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray powder diffraction (XRD). The results demonstrated that the concentration of hydroxyl groups increased after hydrothermal treatment The ability of the titanium surface to form nano-HA was enhanced by increasing the hydrothermal treatment temperature and time. The bonding strength of the formed nano-HA coating, examined by an ultrasonic cleaning process, was higher than that of HA coating generated directly by HA suspension deposition. Culturing of MC3T3-E1 cells on the SLA-Ti and HT-Ti discs in vitro showed that HT-Ti was more favorable for cell attachment and differentiation than SIA-Ti. Hence the one-step hydrothermal treatment with HA suspension was a simple, effective and promising method for HA coating modification of titanium implants. (C) 2010 Elsevier B.V. All rights reserved.