Oscillatory fast wave activity in the rat pyriform cortex: relations to olfaction and behavior
Oscillatory fast wave activity in the rat pyriform cortex: relations to olfaction and behavior
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DOI：
10.1016/s0006-8993(97)00543-x
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发表时间：
1997-08-22
期刊：
影响因子：
2.9
通讯作者：
Vanderwolf, CH
中科院分区：
文献类型：
--
作者：
Zibrowski, EM;Vanderwolf, CH
通过有机溶剂（二甲苯、甲苯、甲基丙烯酸甲酯、松节油）或肛门腺成分的嗅觉刺激，在清醒或乌拉坦麻醉的大鼠（1.25 g/kg，腹膜内）的嗅球和梨状皮层中引发有节奏的快波爆发（> 1 mV，峰值频率近似于 16 Hz；平均频率近似于 20 Hz）大鼠捕食者（2-丙基硫杂环丁烷、黄鼠狼；三甲基噻唑啉、红狐）的分泌物。这些波与嗅觉特别相关，因为它们： fa) 当鼻孔被密封时被阻挡； (b) 不是由非嗅觉刺激引起的； (c) 与并发运动活动无关； (d) 只有当有气味的气流通过鼻道时，才能在麻醉气管切开的大鼠中引起。梨形快波似乎对有机溶剂和捕食者的气味有一定的特异性，因为其他强烈的气味（氨、己酸和丁酸、尸胺）无效。在自然睡眠期间或用氢溴酸东莨菪碱治疗后，低电压梨形背景活动被更大幅度、不规则的 1-20 Hz 波取代。东莨菪碱引起的波不会被自发运动活动所阻断。我们认为梨状皮层，如古皮质和新皮质，接收胆碱能激活输入。 (C) 1997 Elsevier Science B.V.
Bursts of rhythmical fast waves (> 1 mV, peak frequency approximate to 16 Hz; mean frequency approximate to 20 Hz) are elicited in the olfactory bulb and pyriform cortex in waking or urethane-anesthetized rats (1.25 g/kg, i.p.) by olfactory stimulation with organic solvents (xylene, toluene, methyl methacrylate, oil of turpentine) or components of anal gland secretions of rat predators (2-propylthietane, weasel; trimethyl thiazoline, red fox). These waves are specifically related to olfaction since they: fa) are blocked when the nares are sealed; (b) are not elicited by non-olfactory stimuli; (c) are unrelated to concurrent motor activity; and (d) can only be elicited in anesthetized-tracheotomized rats when an odorous airstream is drawn through the nasal passages. Pyriform fast waves appear to be somewhat specific to the odors of organic solvents and predators as other strong odors (ammonia, caproic and butyric acids, cadaverine) are ineffective. During natural sleep or after treatment with scopolamine hydrobromide, low voltage pyriform background activity is replaced by larger amplitude, irregular 1-20 Hz waves. The scopolamine-induced waves are not blocked by spontaneous motor activity. We suggest that the a pyriform cortex, like the archicortex and the neocortex, receives a cholinergic activating input. (C) 1997 Elsevier Science B.V.