Antihypertensive medication withholding practices in hemodialysis: A survey study of patients and providers.
Antihypertensive medication withholding practices in hemodialysis: A survey study of patients and providers.
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血液透析中的抗高血压药物扣留实践：对患者和提供者的调查研究。
DOI：
10.1111/hdi.12640
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Chang,TaraI
中科院分区：
文献类型：
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作者：
Haase,SarahB;Chang,Steven;Schiller,Brigitte;Chertow,GlennM;Chang,TaraI
大多数接受血液透析的患者患有高血压（HTN），需要抗高血压药物治疗1，但治疗可能因溶性低血压（IDH）而受到限制。为了尽量减少IDH，患者经常被告知在血液透析前不要服用降压药；尽管几乎没有证据表明这样做可以减少IDH的发生。此外，它还可能导致长期不受控制的高血压。我们调查了接受血液透析的患者和透析护理提供者，以更好地了解当前的降压药时间实践模式。从2016年9月到2017年1月，在北加州一家中型透析组织接受透析的英语患者，至少服用一种抗高血压药物，被要求完成匿名调查（由研究团队成员管理）。匿名调查以电子方式发送给透析护理提供者，并在当地会议上向提供者分发纸质调查。所有的提供者调查都是自我管理的。我们使用SAS 9.4 （Cary， NC）进行所有分析。p值< 0.05认为有统计学意义。该研究得到了斯坦福机构审查委员会的批准，并获得了同意文件的豁免。
Most patients receiving hemodialysis have hypertension (HTN) requiring antihypertensive medications1, but treatment can be limited by intradialytic hypotension (IDH). To minimize IDH, patients are often told to withhold antihypertensive medications prior to hemodialysis; 2, 3, despite little evidence that doing so reduces the occurrence of IDH. Moreover, it could lead to longer periods of uncontrolled hypertension2. We surveyed patients receiving hemodialysis and dialysis care providers to better understand current antihypertensive medication-timing practice patterns.From September 2016 through January 2017, English-speaking patients receiving dialysis in a medium-sized dialysis organization in Northern California, who took at least one antihypertensive medication were asked to complete the anonymous survey (administered by a research team member). Anonymous surveys were sent electronically to dialysis care providers and paper surveys were distributed to providers at local meetings. All provider surveys were self-administered. We used SAS 9.4 (Cary, NC) for all analyses. A p-value< 0.05 was considered statistically significant. The study was approved by the Stanford Institutional Review Board and a Waiver of Documentation of consent was granted.