Seeing and believing: recent advances in imaging cell-cell interactions.
Seeing and believing: recent advances in imaging cell-cell interactions.
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DOI：
10.12688/f1000research.6435.1
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Parton RG
中科院分区：
文献类型：
--
作者：
Yap AS;Michael M;Parton RG
Advances in cell and developmental biology have often been closely linked to advances in our ability to visualize structure and function at many length and time scales. In this review, we discuss how new imaging technologies and new reagents have provided novel insights into the biology of cadherin-based cell-cell junctions. We focus on three developments: the application of super-resolution optical technologies to characterize the nanoscale organization of cadherins at cell-cell contacts, new approaches to interrogate the mechanical forces that act upon junctions, and advances in electron microscopy which have the potential to transform our understanding of cell-cell junctions.
