Capillary zone electrophoresis with electrochemical detection in 12.7 microns diameter columns.
Capillary zone electrophoresis with electrochemical detection in 12.7 microns diameter columns.
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DOI：
10.1021/ac00169a027
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发表时间：
1988-09
影响因子：
7.4
通讯作者：
R. A. Wallingford;A. Ewing
中科院分区：
文献类型：
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作者：
R. A. Wallingford;A. Ewing
区电泳毛细管（1-19）已成为一个迅速发展的研究领域。这种技术被称为毛细管区带电泳（CZE），采用极高的电位场导致离子溶质的高效分离。高效结合处理超小体积样品的能力使CZE成为许多生物分离的有吸引力的方法。由于玻璃（1- 5,7）和熔融二氧化硅（8,10 -19）毛细管提供的高效散热，高电位可以应用于缓冲填充的毛细血管。迄今为止报道的CZE工作使用的毛细血管直径范围为25（8,19）至500 pm(1)，其中50-80 pm最大
Sir: Zone electrophoresisin capillaries (1-19) has become a rapidly developing field of research. This technique, termed capillary zone electrophoresis (CZE), employs extremely high potential fields resulting in highly efficient separations of ionic solutes. High efficiency combined with the ability to handle ultrasmall volume samples make CZE an attractive method for many biological separations.High potentials can be applied across buffer-filled capillaries due to the efficient heat dissipation afforded by glass (1-5, 7) and fused silica (8, 10-19) capillaries. CZE work reported to date has employed capillaries having bore diameters ranging from 25 (8, 19) to 500 pm (1), with 50-80 pm being most