Incidence and toxicological aspects of drugs detected in 484 fatally injured drivers and pedestrians in Ontario.
Incidence and toxicological aspects of drugs detected in 484 fatally injured drivers and pedestrians in Ontario.
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在安大略省 484 名受伤的司机和行人中检测到的药物的发生率和毒理学方面。
DOI：
10.1520/jfs12203j
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发表时间：
1982
影响因子：
1.6
通讯作者：
H. Simpson
中科院分区：
文献类型：
--
作者：
G. Cimbura;D. Lucas;R. C. Bennett;R. Warren;H. Simpson
结果提出了一个全面的药物研究进行的标本从司机和行人在安大略致命受伤。定期对血液和尿液以及偶尔对玻璃体液、胃内容物和肝脏进行毒理学分析。分析程序可以检测和定量多种药物，包括大麻等非法药物。在司机方面，57%的研究样本中发现了酒精，26%的样本中发现了酒精以外的药物。然而，只有9.5%的司机在血液中检测到精神药物（酒精除外），其浓度可能对驾驶技能产生不利影响。δ-9-四氢大麻酚和地西泮占这一类别中的大多数发现。
Results are presented of a comprehensive drug study carried out on specimens from drivers and pedestrians fatally injured in Ontario. Toxicological analyses were regularly performed on blood and urine and occasionally on vitreous humor, stomach contents, and liver. The analytical procedures could detect and quantitate a wide variety of drugs including such illicit drugs as Cannabis. With respect to drivers, alcohol was found in 57% of the study sample and drugs other than alcohol, in 26%. However, in only 9.5% of the drivers were psychoactive drugs (other than alcohol) detected in the blood in concentrations that may adversely affect driving skills. Delta-9-Tetrahydrocannabinol and diazepam accounted for a majority of the findings in this category.