Robot-assisted gait training for balance and lower extremity function in patients with infratentorial stroke: a single-blinded randomized controlled trial
Robot-assisted gait training for balance and lower extremity function in patients with infratentorial stroke: a single-blinded randomized controlled trial
复制标题
机器人辅助步态训练对幕下脑卒中患者平衡及下肢功能的影响：一项单盲随机对照试验
DOI：
10.1186/s12984-019-0553-5
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发表时间：
2019-07-29
影响因子：
5.1
通讯作者：
Lee, Stephanie Hyeyoung
中科院分区：
文献类型：
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作者：
Kim, Ha Yeon;Shin, Joon-Ho;Lee, Stephanie Hyeyoung
背景平衡障碍在幕下卒中患者中很常见。尽管机器人辅助步态训练（RAGT）对中风患者的平衡能力产生积极影响，但目前尚不清楚这种训练是否优于传统物理治疗（CPT）。因此，我们旨在探讨RAGT联合CPT的效果，并与仅CPT对幕下卒中幸存者平衡和下肢功能的影响进行比较。方法本研究是一项单盲、交叉设计的随机对照试验，在一家康复医院进行。幕下卒中患者（n=19；16 名男性，3 名女性；平均年龄：47.411.6 岁）被随机分配到 A 组（4 周 RAGT+CPT，随后 4 周 CPT+CPT）或 B 组（4 周 CPT+CPT，随后 4 周 RAGT+CPT）。伯格平衡量表分数表明的动态和静态平衡的变化被视为主要结果指标。在基线时和每 4 周干预期后对每位参与者的结果测量进行评估。结果 A 组和 B 组在基线时未观察到结果相关变量存在显着差异。此外，没有观察到任何变量存在显着的逐组时间交互作用，这表明干预顺序对下肢功能或平衡没有影响。与 CPT+CPT 干预相比，RAGT+CPT 干预后观察到次要功能结果（例如下肢 Fugl-Meyer 评估 (FMA-LE) 和共济失调评估和评级量表 (SARA)）显着改善。结论 RAGT 对幕下卒中个体的平衡和下肢功能产生临床显着改善。因此，RAGT 对于继发于其他病理的平衡障碍的患者可能有用。试验注册 p id=Par5 ClinicalTrials.gov 标识符 NCT02680691。 2016 年 2 月 9 日注册；追溯注册。
BackgroundBalance impairments are common in patients with infratentorial stroke. Although robot-assisted gait training (RAGT) exerts positive effects on balance among patients with stroke, it remains unclear whether such training is superior to conventional physical therapy (CPT). Therefore, we aimed to investigate the effects of RAGT combined with CPT and compared them with the effects of CPT only on balance and lower extremity function among survivors of infratentorial stroke.MethodsThis study was a single-blinded, randomized controlled trial with a crossover design conducted at a single rehabilitation hospital. Patients (n=19; 16 men, three women; mean age: 47.411.6years) with infratentorial stroke were randomly allocated to either group A (4weeks of RAGT+CPT, followed by 4weeks of CPT+CPT) or group B (4weeks of CPT+CPT followed by 4weeks of RAGT+CPT). Changes in dynamic and static balance as indicated by Berg Balance Scale scores were regarded as the primary outcome measure. Outcome measures were evaluated for each participant at baseline and after each 4-week intervention period.ResultsNo significant differences in outcome-related variables were observed between group A and B at baseline. In addition, no significant time-by-group interactions were observed for any variables, indicating that intervention order had no effect on lower extremity function or balance. Significantly greater improvements in secondary functional outcomes such as lower extremity Fugl-Meyer assessment (FMA-LE) and scale for the assessment and rating of ataxia (SARA) were observed following the RAGT+CPT intervention than following the CPT+CPT intervention.ConclusionRAGT produces clinically significant improvements in balance and lower extremity function in individuals with infratentorial stroke. Thus, RAGT may be useful for patients with balance impairments secondary to other pathologies.Trial registration p id=Par5 ClinicalTrials.gov Identifier NCT02680691. Registered 09 February 2016; retrospectively registered.